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Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

peptidyl-glutaminase (EC 3.5.1.43)

peptidyl-glutaminase. EC 3.5.1.43.. [protein]-C-terminal-L-glutamine + H2O = [protein]-C-terminal-L-glutamate

peptidyl-glycinamidase (EC 3.4.19.2)

peptidyl-glycinamidase. EC 3.4.19.2.. Cleavage of C-terminal glycinamide from polypeptides.

peptidyl-Lys metalloendopeptidase (EC 3.4.24.20)

peptidyl-Lys metalloendopeptidase. EC 3.4.24.20.. Preferential cleavage in proteins: -Xaa-|-Lys- (in which Xaa may be Pro).

peptidyl-lysine (3S)-dioxygenase (EC 1.14.11.63)

peptidyl-lysine (3S)-dioxygenase. EC 1.14.11.63.. L-lysyl-[protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-lysyl-

peptidyl-tRNA hydrolase (EC 3.1.1.29)

peptidyl-tRNA hydrolase. EC 3.1.1.29.. an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA

peptidylamidoglycolate lyase (EC 4.3.2.5)

peptidylamidoglycolate lyase. EC 4.3.2.5.. a [peptide]-C-terminal (2S)-2-hydroxyglycine = a [peptide]-C-terminal

peptidylglycine monooxygenase (EC 1.14.17.3)

peptidylglycine monooxygenase. EC 1.14.17.3.. a [peptide]-C-terminal glycine + 2 L-ascorbate + O2 = a [peptide]-C-

peptidylprolyl isomerase (EC 5.2.1.8)

peptidylprolyl isomerase. EC 5.2.1.8.. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline

peptidyltransferase (EC 2.3.2.12)

peptidyltransferase. EC 2.3.2.12.. peptidyl-tRNA1 + aminoacyl-tRNA2 = tRNA1 + peptidyl(aminoacyl-tRNA2).

perakine reductase (EC 1.1.1.317)

perakine reductase. EC 1.1.1.317.. raucaffrinoline + NADP(+) = perakine + NADPH + H(+).

peregrinol diphosphate synthase (EC 4.2.1.174)

peregrinol diphosphate synthase. EC 4.2.1.174.. peregrinol diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + H2O.

perillyl-alcohol dehydrogenase (EC 1.1.1.144)

perillyl-alcohol dehydrogenase. EC 1.1.1.144.. perillyl alcohol + NAD(+) = perillyl aldehyde + NADH + H(+).

peroxidase (EC 1.11.1.7)

peroxidase. EC 1.11.1.7.. 2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O.

peroxisome-assembly ATPase (EC 3.6.4.7)

peroxisome-assembly ATPase. EC 3.6.4.7.. ATP + H2O = ADP + phosphate + H(+).

persulfide dioxygenase (EC 1.13.11.18)

persulfide dioxygenase. EC 1.13.11.18.. S-sulfanylglutathione + O2 + H2O = sulfite + glutathione + 2 H(+).

pestivirus NS3 polyprotein peptidase (EC 3.4.21.113)

pestivirus NS3 polyprotein peptidase. EC 3.4.21.113.. Leu is conserved at position P1 for all four cleavage sites. Alanine is

petromyzonol sulfotransferase (EC 2.8.2.31)

petromyzonol sulfotransferase. EC 2.8.2.31.. 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol + 3'-phosphoadenylyl

phaseollidin hydratase (EC 4.2.1.97)

phaseollidin hydratase. EC 4.2.1.97.. phaseollidin hydrate = phaseollidin + H2O.

phenacrylate decarboxylase (EC 4.1.1.102)

phenacrylate decarboxylase. EC 4.1.1.102.. (1) (E)-4-coumarate + H(+) = 4-vinylphenol + CO2.

phenazine-1-carboxylate N-methyltransferase (EC 2.1.1.327)

phenazine-1-carboxylate N-methyltransferase. EC 2.1.1.327.. phenazine-1-carboxylate + S-adenosyl-L-methionine = 5-methyl-phenazine-1-

phenol 2-monooxygenase (FADH2) (EC 1.14.14.20)

phenol 2-monooxygenase (FADH2). EC 1.14.14.20.. phenol + FADH2 + O2 = catechol + FAD + H2O + H(+).

phenol 2-monooxygenase (NADH) (EC 1.14.13.244)

phenol 2-monooxygenase (NADH). EC 1.14.13.244.. phenol + NADH + O2 + H(+) = catechol + NAD(+) + H2O.

phenol 2-monooxygenase (NADPH) (EC 1.14.13.7)

phenol 2-monooxygenase (NADPH). EC 1.14.13.7.. phenol + NADPH + O2 + H(+) = catechol + NADP(+) + H2O.

phenol beta-glucosyltransferase (EC 2.4.1.35)

phenol beta-glucosyltransferase. EC 2.4.1.35.. UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside.

phenol O-methyltransferase (EC 2.1.1.25)

phenol O-methyltransferase. EC 2.1.1.25.. phenol + S-adenosyl-L-methionine = anisole + S-adenosyl-L-homocysteine +

phenol phosphorylase (EC 2.7.1.238)

phenol phosphorylase. EC 2.7.1.238.. phenol + ATP + H2O = phenyl phosphate + AMP + phosphate + 2 H(+).

phenolphthiocerol/phthiocerol/phthiodiolone dimycocerosyl transferase (EC 2.3.1.282)

phenolphthiocerol/phthiocerol/phthiodiolone dimycocerosyl transferase. EC 2.3.1.282.. (1) 2 a mycocerosyl-[mycocerosic acid synthase] + a phthiocerol =

phenyl-N-(sulfonatooxy)methanimidothioate sulfolyase (EC 4.8.1.7)

phenyl-N-(sulfonatooxy)methanimidothioate sulfolyase. EC 4.8.1.7.. (Z)-phenyl-N-(sulfonatooxy)methanimidothioate = benzyl thiocyanate +

phenyl-phosphate phosphatase/carboxylase (EC 4.1.1.123)

phenyl-phosphate phosphatase/carboxylase. EC 4.1.1.123.. 4-hydroxybenzoate + phosphate + H(+) = phenyl phosphate + CO2 + H2O.

phenylacetaldehyde dehydrogenase (EC 1.2.1.39)

phenylacetaldehyde dehydrogenase. EC 1.2.1.39.. 2-phenylacetaldehyde + NAD(+) + H2O = 2-phenylacetate + NADH + 2 H(+).

phenylacetaldehyde oxime monooxygenase (EC 1.14.14.44)

phenylacetaldehyde oxime monooxygenase. EC 1.14.14.44.. (E)-phenylacetaldehyde oxime + reduced [NADPH--hemoprotein reductase] +

phenylacetaldehyde synthase (EC 4.1.1.109)

phenylacetaldehyde synthase. EC 4.1.1.109.. L-phenylalanine + O2 + H2O + H(+) = 2-phenylacetaldehyde + H2O2 +

phenylacetaldoxime dehydratase (EC 4.8.1.4)

phenylacetaldoxime dehydratase. EC 4.8.1.4.. (Z)-phenylacetaldehyde oxime = phenylacetonitrile + H2O.

phenylacetate 2-hydroxylase (EC 1.14.14.54)

phenylacetate 2-hydroxylase. EC 1.14.14.54.. 2-phenylacetate + reduced [NADPH--hemoprotein reductase] + O2 =

phenylacetate decarboxylase (EC 4.1.1.119)

phenylacetate decarboxylase. EC 4.1.1.119.. 2-phenylacetate + H(+) = toluene + CO2.

phenylacetate--CoA ligase (EC 6.2.1.30)

phenylacetate--CoA ligase. EC 6.2.1.30.. 2-phenylacetate + ATP + CoA = phenylacetyl-CoA + AMP + diphosphate.

phenylacetone monooxygenase (EC 1.14.13.92)

phenylacetone monooxygenase. EC 1.14.13.92.. phenylacetone + NADPH + O2 + H(+) = benzyl acetate + NADP(+) + H2O.

phenylacetonitrile alpha-monooxygenase (EC 1.14.14.77)

phenylacetonitrile alpha-monooxygenase. EC 1.14.14.77.. phenylacetonitrile + reduced [NADPH--hemoprotein reductase] + O2 = (R)-

phenylacetyl-CoA 1,2-epoxidase (EC 1.14.13.149)

phenylacetyl-CoA 1,2-epoxidase. EC 1.14.13.149.. phenylacetyl-CoA + NADPH + O2 + H(+) = 2-(1,2-epoxy-1,2-

phenylacetyl-CoA dehydrogenase (EC 1.17.5.1)

phenylacetyl-CoA dehydrogenase. EC 1.17.5.1.. phenylacetyl-CoA + 2 a ubiquinone + H2O = phenylglyoxylyl-CoA + 2 a

phenylacetyl-CoA hydrolase (EC 3.1.2.25)

phenylacetyl-CoA hydrolase. EC 3.1.2.25.. phenylglyoxylyl-CoA + H2O = phenylglyoxylate + CoA + H(+).

phenylalanine 2-monooxygenase (EC 1.13.12.9)

phenylalanine 2-monooxygenase. EC 1.13.12.9.. L-phenylalanine + O2 = 2-phenylacetamide + CO2 + H2O.

phenylalanine 3-monooxygenase (EC 1.14.16.7)

phenylalanine 3-monooxygenase. EC 1.14.16.7.. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 =

phenylalanine 4-monooxygenase (EC 1.14.16.1)

phenylalanine 4-monooxygenase. EC 1.14.16.1.. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 =

phenylalanine aminomutase (D-beta-phenylalanine forming) (EC 5.4.3.11)

phenylalanine aminomutase (D-beta-phenylalanine forming). EC 5.4.3.11.. L-phenylalanine = (S)-3-amino-3-phenylpropanoate.

phenylalanine aminomutase (L-beta-phenylalanine forming) (EC 5.4.3.10)

phenylalanine aminomutase (L-beta-phenylalanine forming). EC 5.4.3.10.. L-phenylalanine = (3R)-beta-phenylalanine.

phenylalanine ammonia-lyase (EC 4.3.1.24)

phenylalanine ammonia-lyase. EC 4.3.1.24.. L-phenylalanine = (E)-cinnamate + NH4(+).

phenylalanine decarboxylase (EC 4.1.1.53)

phenylalanine decarboxylase. EC 4.1.1.53.. L-phenylalanine + H(+) = 2-phenylethylamine + CO2.

phenylalanine dehydrogenase (EC 1.4.1.20)

phenylalanine dehydrogenase. EC 1.4.1.20.. L-phenylalanine + NAD(+) + H2O = 3-phenylpyruvate + NH4(+) + NADH + H(+).

phenylalanine N-acetyltransferase (EC 2.3.1.53)

phenylalanine N-acetyltransferase. EC 2.3.1.53.. L-phenylalanine + acetyl-CoA = N-acetyl-L-phenylalanine + CoA + H(+).

phenylalanine N-monooxygenase (EC 1.14.14.40)

phenylalanine N-monooxygenase. EC 1.14.14.40.. L-phenylalanine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = (E)-

phenylalanine racemase (ATP-hydrolyzing) (EC 5.1.1.11)

phenylalanine racemase (ATP-hydrolyzing). EC 5.1.1.11.. L-phenylalanine + ATP + H2O = D-phenylalanine + AMP + diphosphate + H(+).

phenylalanine--tRNA ligase (EC 6.1.1.20)

phenylalanine--tRNA ligase. EC 6.1.1.20.. tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP +

phenylalanine(histidine) transaminase (EC 2.6.1.58)

phenylalanine(histidine) transaminase. EC 2.6.1.58.. L-phenylalanine + pyruvate = 3-phenylpyruvate + L-alanine.

phenylalanine/tyrosine ammonia-lyase (EC 4.3.1.25)

phenylalanine/tyrosine ammonia-lyase. EC 4.3.1.25.. (1) L-phenylalanine = (E)-cinnamate + NH4(+).

phenylethanolamine N-methyltransferase (EC 2.1.1.28)

phenylethanolamine N-methyltransferase. EC 2.1.1.28.. phenylethanolamine + S-adenosyl-L-methionine = N-methylphenylethanolamine

phenylglycine N-acetyltransferase (EC 2.3.1.331)

phenylglycine N-acetyltransferase. EC 2.3.1.331.. L-alpha-phenylglycine + acetyl-CoA = N-acetyl-L-alpha-phenylglycine +

phenylglyoxylate dehydrogenase (acylating) (EC 1.2.1.58)

phenylglyoxylate dehydrogenase (acylating). EC 1.2.1.58.. phenylglyoxylate + NAD(+) + CoA = benzoyl-CoA + CO2 + NADH.

phenyllactate glucosyltransferase (EC 2.4.1.399)

phenyllactate glucosyltransferase. EC 2.4.1.399.. (R)-3-phenyllactate + UDP-alpha-D-glucose = (R)-3-phenyllactyl-beta-D-

phenylpropanoylacetyl-CoA synthase (EC 2.3.1.218)

phenylpropanoylacetyl-CoA synthase. EC 2.3.1.218.. (1) (E)-feruloyl-CoA + malonyl-CoA + H(+) = (E)-feruloylacetyl-CoA +