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Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

methylene-fatty-acyl-phospholipid synthase (EC 2.1.1.16)

methylene-fatty-acyl-phospholipid synthase. EC 2.1.1.16.. a 1-acyl-2-(9Z)-enoyl-sn-glycero-3-phospholipid + S-adenosyl-L-methionine

methylenediurea deaminase (EC 3.5.3.21)

methylenediurea deaminase. EC 3.5.3.21.. methylenediurea + 2 H2O + 2 H(+) = N-(hydroxymethyl)urea + 2 NH4(+) +

methylenetetrahydrofolate dehydrogenase (NAD(+)) (EC 1.5.1.15)

methylenetetrahydrofolate dehydrogenase (NAD(+)). EC 1.5.1.15.. (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-

methylenetetrahydrofolate dehydrogenase (NADP(+)) (EC 1.5.1.5)

methylenetetrahydrofolate dehydrogenase (NADP(+)). EC 1.5.1.5.. (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-

methylenetetrahydrofolate reductase (ferredoxin) (EC 1.5.7.1)

methylenetetrahydrofolate reductase (ferredoxin). EC 1.5.7.1.. (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 2 oxidized [2Fe-2S]-[ferredoxin]

methylenetetrahydrofolate reductase (NADH) (EC 1.5.1.54)

methylenetetrahydrofolate reductase (NADH). EC 1.5.1.54.. (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-

methylenetetrahydrofolate reductase (NADPH) (EC 1.5.1.53)

methylenetetrahydrofolate reductase (NADPH). EC 1.5.1.53.. (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-

methylenetetrahydrofolate reductase [NAD(P)H] (EC 1.5.1.20)

methylenetetrahydrofolate reductase [NAD(P)H]. EC 1.5.1.20.. (1) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-

methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-methyltransferase (EC 2.1.1.74)

methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-methyltransferase. EC 2.1.1.74.. (1) uridine(54) in tRNA + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate +

methylenetetrahydromethanopterin dehydrogenase (EC 1.5.98.1)

methylenetetrahydromethanopterin dehydrogenase. EC 1.5.98.1.. 5,10-methylenetetrahydromethanopterin + oxidized coenzyme F420-(gamma-L-

methylglutaconyl-CoA hydratase (EC 4.2.1.18)

methylglutaconyl-CoA hydratase. EC 4.2.1.18.. (3S)-3-hydroxy-3-methylglutaryl-CoA = 3-methyl-(2E)-glutaconyl-CoA + H2O.

methylglutamate dehydrogenase (EC 1.5.99.5)

methylglutamate dehydrogenase. EC 1.5.99.5.. N-methyl-L-glutamate + A + H2O = formaldehyde + L-glutamate + AH2.

methylglyoxal reductase (NADH) (EC 1.1.1.78)

methylglyoxal reductase (NADH). EC 1.1.1.78.. (R)-lactaldehyde + NAD(+) = methylglyoxal + NADH + H(+).

methylglyoxal reductase (NADPH) (EC 1.1.1.283)

methylglyoxal reductase (NADPH). EC 1.1.1.283.. (S)-lactaldehyde + NADP(+) = methylglyoxal + NADPH + H(+).

methylglyoxal synthase (EC 4.2.3.3)

methylglyoxal synthase. EC 4.2.3.3.. dihydroxyacetone phosphate = methylglyoxal + phosphate.

methylguanidinase (EC 3.5.3.16)

methylguanidinase. EC 3.5.3.16.. methylguanidine + H2O = urea + methylamine.

methylisocitrate lyase (EC 4.1.3.30)

methylisocitrate lyase. EC 4.1.3.30.. (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate.

methylitaconate Delta-isomerase (EC 5.3.3.6)

methylitaconate Delta-isomerase. EC 5.3.3.6.. 2-methylene-3-methylsuccinate = dimethylmaleate.

methylmalonate-semialdehyde dehydrogenase (CoA acylating) (EC 1.2.1.27)

methylmalonate-semialdehyde dehydrogenase (CoA acylating). EC 1.2.1.27.. 2-methyl-3-oxopropanoate + NAD(+) + CoA + H2O = propanoyl-CoA +

methylmalonyl-CoA carboxytransferase (EC 2.1.3.1)

methylmalonyl-CoA carboxytransferase. EC 2.1.3.1.. (S)-methylmalonyl-CoA + pyruvate = propanoyl-CoA + oxaloacetate.

methylmalonyl-CoA epimerase (EC 5.1.99.1)

methylmalonyl-CoA epimerase. EC 5.1.99.1.. (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA.

methylmalonyl-CoA mutase (EC 5.4.99.2)

methylmalonyl-CoA mutase. EC 5.4.99.2.. (R)-methylmalonyl-CoA = succinyl-CoA.

methylornithine synthase (EC 5.4.99.58)

methylornithine synthase. EC 5.4.99.58.. L-lysine = (3R)-3-methyl-D-ornithine.

methylphosphonate hydroxylase (EC 1.14.11.71)

methylphosphonate hydroxylase. EC 1.14.11.71.. methylphosphonate + 2-oxoglutarate + O2 = hydroxymethylphosphonate +

methylphosphonate synthase (EC 1.13.11.73)

methylphosphonate synthase. EC 1.13.11.73.. 2-hydroxyethylphosphonate + O2 = methylphosphonate + hydrogencarbonate +

methylphosphothioglycerate phosphatase (EC 3.1.3.14)

methylphosphothioglycerate phosphatase. EC 3.1.3.14.. (2R)-S-methyl-3-phospho-1-thioglycerate + H2O = (2R)-S-methyl-1-

methylphosphotriester-DNA--[protein]-cysteine S-methyltransferase (EC 2.1.1.n11)

methylphosphotriester-DNA--[protein]-cysteine S-methyltransferase. EC 2.1.1.n11.. (2'-deoxyribonucleoside 5'-methylphosphotriester)-DNA + L-cysteinyl-

methylquercetagetin 6-O-methyltransferase (EC 2.1.1.84)

methylquercetagetin 6-O-methyltransferase. EC 2.1.1.84.. 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine =

methyltetrahydroprotoberberine 14-monooxygenase (EC 1.14.14.97)

methyltetrahydroprotoberberine 14-monooxygenase. EC 1.14.14.97.. (1) (S)-cis-N-methylcanadine + reduced [NADPH--hemoprotein reductase] +

methylthioacryloyl-CoA hydratase (EC 4.2.1.155)

methylthioacryloyl-CoA hydratase. EC 4.2.1.155.. 3-(methylsulfanyl)acryloyl-CoA + 2 H2O = methanethiol + acetaldehyde +

methylthioadenosine nucleosidase (EC 3.2.2.16)

methylthioadenosine nucleosidase. EC 3.2.2.16.. S-methyl-5'-thioadenosine + H2O = 5-(methylsulfanyl)-D-ribose + adenine.

methylthioalkylmalate synthase (EC 2.3.3.17)

methylthioalkylmalate synthase. EC 2.3.3.17.. an omega-(methylsulfanyl)-2-oxoalkanoate + acetyl-CoA + H2O = a 2-(omega-

methylthioribulose 1-phosphate dehydratase (EC 4.2.1.109)

methylthioribulose 1-phosphate dehydratase. EC 4.2.1.109.. 5-(methylsulfanyl)-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-

methyltransferase cap1 (EC 2.1.1.57)

methyltransferase cap1. EC 2.1.1.57.. a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA +

methyltransferase cap2 (EC 2.1.1.296)

methyltransferase cap2. EC 2.1.1.296.. a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-

methylumbelliferyl-acetate deacetylase (EC 3.1.1.56)

methylumbelliferyl-acetate deacetylase. EC 3.1.1.56.. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate +

methylxanthine N(1)-demethylase (EC 1.14.13.178)

methylxanthine N(1)-demethylase. EC 1.14.13.178.. (1) caffeine + NADH + O2 + H(+) = theobromine + formaldehyde + NAD(+) +

methylxanthine N(3)-demethylase (EC 1.14.13.179)

methylxanthine N(3)-demethylase. EC 1.14.13.179.. (1) theobromine + NADH + O2 + H(+) = 7-methylxanthine + formaldehyde +

metridin (EC 3.4.21.3)

metridin. EC 3.4.21.3.. Preferential cleavage: Tyr-|-Xaa, Phe-|-Xaa, Leu-|-Xaa. Little action on

mevalonate 3-kinase (EC 2.7.1.185)

mevalonate 3-kinase. EC 2.7.1.185.. (R)-mevalonate + ATP = (R)-3-phosphomevalonate + ADP + H(+).

mevalonate kinase (EC 2.7.1.36)

mevalonate kinase. EC 2.7.1.36.. (R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + H(+).

mevalonate-3-phosphate 5-kinase (EC 2.7.1.186)

mevalonate-3-phosphate 5-kinase. EC 2.7.1.186.. (R)-3-phosphomevalonate + ATP = (R)-3,5-bisphosphomevalonate + ADP +

microbial collagenase (EC 3.4.24.3)

microbial collagenase. EC 3.4.24.3.. Digestion of native collagen in the triple helical region at Xaa-|-Gly

micrococcal nuclease (EC 3.1.31.1)

micrococcal nuclease. EC 3.1.31.1.. Endonucleolytic cleavage to nucleoside 3'-phosphates and

microsomal epoxide hydrolase (EC 3.3.2.9)

microsomal epoxide hydrolase. EC 3.3.2.9.. (1) cis-stilbene oxide + H2O = (1R,2R)-hydrobenzoin.

microtubule-severing ATPase (EC 5.6.1.1)

microtubule-severing ATPase. EC 5.6.1.1.. n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta

miltiradiene synthase (EC 4.2.3.131)

miltiradiene synthase. EC 4.2.3.131.. (+)-copalyl diphosphate = miltiradiene + diphosphate.

mimosinase (EC 4.3.3.8)

mimosinase. EC 4.3.3.8.. L-mimosine + H2O = 3-hydroxy-4H-pyrid-4-one + pyruvate + NH4(+).

minus-end-directed kinesin ATPase (EC 5.6.1.4)

minus-end-directed kinesin ATPase. EC 5.6.1.4.. ATP + H2O + a kinesin associated with a microtubule at position (n) =

mitochondrial intermediate peptidase (EC 3.4.24.59)

mitochondrial intermediate peptidase. EC 3.4.24.59.. Release of an N-terminal octapeptide as second stage of processing of

mitochondrial processing peptidase (EC 3.4.24.64)

mitochondrial processing peptidase. EC 3.4.24.64.. Release of N-terminal transit peptides from precursor proteins imported

mitochondrial protein-transporting ATPase (EC 7.4.2.3)

mitochondrial protein-transporting ATPase. EC 7.4.2.3.. ATP + H2O + mitochondrial-proteinSide 1 = ADP + phosphate +

mitochondrial tRNA pseudouridine(27/28) synthase (EC 5.4.99.44)

mitochondrial tRNA pseudouridine(27/28) synthase. EC 5.4.99.44.. uridine(27/28) in mitochondrial tRNA = pseudouridine(27/28) in

mitogen-activated protein kinase (EC 2.7.11.24)

mitogen-activated protein kinase. EC 2.7.11.24.. (1) L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).

mitogen-activated protein kinase kinase (EC 2.7.12.2)

mitogen-activated protein kinase kinase. EC 2.7.12.2.. (1) L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).

mitogen-activated protein kinase kinase kinase (EC 2.7.11.25)

mitogen-activated protein kinase kinase kinase. EC 2.7.11.25.. (1) L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).

mitomycin 6-O-methyltransferase (EC 2.1.1.316)

mitomycin 6-O-methyltransferase. EC 2.1.1.316.. (1) 6-demethylmitomycin A + S-adenosyl-L-methionine = mitomycin A +

MMP 1-O-methyltransferase (EC 2.1.1.365)

MMP 1-O-methyltransferase. EC 2.1.1.365.. 3,3'-di-O-methyl-4alpha-mannobiose + S-adenosyl-L-methionine =

MMP alpha-(1->4)-mannosyltransferase (EC 2.4.1.393)

MMP alpha-(1->4)-mannosyltransferase. EC 2.4.1.393.. [3-O-methyl-alpha-D-mannosyl-(1->4)](n)-3-O-methyl-D-mannose + GDP-alpha-

MMP endo-(1,4)-3-O-methyl-alpha-D-mannosidase (EC 3.2.1.221)

MMP endo-(1,4)-3-O-methyl-alpha-D-mannosidase. EC 3.2.1.221.. Endohydrolysis of 3-O-methyl-alpha-D-mannosyl-(1->4)-3-O-methyl-D-mannose