Biochemistry & Enzymes

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Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

lysophospholipase (EC 3.1.1.5)

lysophospholipase. EC 3.1.1.5.. a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine

lysoplasmalogenase (EC 3.3.2.2)

lysoplasmalogenase. EC 3.3.2.2.. (1) a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O = a 2,3-

lysosomal Pro-Xaa carboxypeptidase (EC 3.4.16.2)

lysosomal Pro-Xaa carboxypeptidase. EC 3.4.16.2.. Cleavage of a -Pro-|-Xaa bond to release a C-terminal amino acid.

lysostaphin (EC 3.4.24.75)

lysostaphin. EC 3.4.24.75.. Hydrolysis of the -Gly-|-Gly- bond in the pentaglycine inter-peptide link

lysozyme (EC 3.2.1.17)

lysozyme. EC 3.2.1.17.. Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and

lysyl endopeptidase (EC 3.4.21.50)

lysyl endopeptidase. EC 3.4.21.50.. Preferential cleavage: Lys-|-Xaa, including Lys-|-Pro.

lysyltransferase (EC 2.3.2.3)

lysyltransferase. EC 2.3.2.3.. L-lysyl-tRNA(Lys) + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) =

lytic cellulose monooxygenase (C1-hydroxylating) (EC 1.14.99.54)

lytic cellulose monooxygenase (C1-hydroxylating). EC 1.14.99.54.. [(1->4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = [(1->4)-beta-D-

lytic cellulose monooxygenase (C4-dehydrogenating) (EC 1.14.99.56)

lytic cellulose monooxygenase (C4-dehydrogenating). EC 1.14.99.56.. [(1->4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-

lytic chitin monooxygenase (EC 1.14.99.53)

lytic chitin monooxygenase. EC 1.14.99.53.. [(1->4)-N-acetyl-beta-D-glucosaminyl]n+m + reduced acceptor + O2 =

lytic starch monooxygenase (EC 1.14.99.55)

lytic starch monooxygenase. EC 1.14.99.55.. starch + reduced acceptor + O2 = D-glucono-1,5-lactone-terminated malto-

macrocin O-methyltransferase (EC 2.1.1.101)

macrocin O-methyltransferase. EC 2.1.1.101.. macrocin + S-adenosyl-L-methionine = tylosin + S-adenosyl-L-homocysteine

macrolide 2'-kinase (EC 2.7.1.136)

macrolide 2'-kinase. EC 2.7.1.136.. oleandomycin + ATP = oleandomycin 2'-O-phosphate + ADP + H(+).

macrophage elastase (EC 3.4.24.65)

macrophage elastase. EC 3.4.24.65.. Hydrolysis of soluble and insoluble elastin. Specific cleavages are also

macrophomene synthase (EC 4.2.3.221)

macrophomene synthase. EC 4.2.3.221.. all-trans-hexaprenyl diphosphate = macrophomene + diphosphate.

magnesium chelatase (EC 6.6.1.1)

magnesium chelatase. EC 6.6.1.1.. protoporphyrin IX + Mg(2+) + ATP + H2O = Mg-protoporphyrin IX + ADP +

magnesium dechelatase (EC 4.99.1.10)

magnesium dechelatase. EC 4.99.1.10.. (1) chlorophyll a + 2 H(+) = pheophytin a + Mg(2+).

magnesium protoporphyrin IX methyltransferase (EC 2.1.1.11)

magnesium protoporphyrin IX methyltransferase. EC 2.1.1.11.. Mg-protoporphyrin IX + S-adenosyl-L-methionine = Mg-protoporphyrin IX

magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase (EC 1.14.13.81)

magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase. EC 1.14.13.81.. Mg-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 O2 + 2 H(+) = 3,8-

magnolysin (EC 3.4.24.62)

magnolysin. EC 3.4.24.62.. Hydrolysis of polypeptides with Arg or Lys in P1 and P2, e.g. to

malate dehydrogenase (decarboxylating) (EC 1.1.1.39)

malate dehydrogenase (decarboxylating). EC 1.1.1.39.. (S)-malate + NAD(+) = pyruvate + CO2 + NADH.

malate dehydrogenase (NADP(+)) (EC 1.1.1.82)

malate dehydrogenase (NADP(+)). EC 1.1.1.82.. (S)-malate + NADP(+) = oxaloacetate + NADPH + H(+).

malate dehydrogenase (oxaloacetate-decarboxylating) (EC 1.1.1.38)

malate dehydrogenase (oxaloacetate-decarboxylating). EC 1.1.1.38.. (1) (S)-malate + NAD(+) = pyruvate + CO2 + NADH.

malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (EC 1.1.1.40)

malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). EC 1.1.1.40.. (1) (S)-malate + NADP(+) = pyruvate + CO2 + NADPH.

malate dehydrogenase (quinone) (EC 1.1.5.4)

malate dehydrogenase (quinone). EC 1.1.5.4.. (S)-malate + a quinone = a quinol + oxaloacetate.

malate dehydrogenase [NAD(P)(+)] (EC 1.1.1.299)

malate dehydrogenase [NAD(P)(+)]. EC 1.1.1.299.. (1) (S)-malate + NAD(+) = oxaloacetate + NADH + H(+).

malate synthase (EC 2.3.3.9)

malate synthase. EC 2.3.3.9.. glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+).

malate--CoA ligase (EC 6.2.1.9)

malate--CoA ligase. EC 6.2.1.9.. (S)-malate + ATP + CoA = (S)-malyl-CoA + ADP + phosphate.

maleamate amidohydrolase (EC 3.5.1.107)

maleamate amidohydrolase. EC 3.5.1.107.. maleamate + H2O = maleate + NH4(+).

maleate hydratase (EC 4.2.1.31)

maleate hydratase. EC 4.2.1.31.. (R)-malate = maleate + H2O.

maleate isomerase (EC 5.2.1.1)

maleate isomerase. EC 5.2.1.1.. maleate = fumarate.

maleimide hydrolase (EC 3.5.2.16)

maleimide hydrolase. EC 3.5.2.16.. maleimide + H2O = maleamate + H(+).

maleylacetate reductase (EC 1.3.1.32)

maleylacetate reductase. EC 1.3.1.32.. (1) 3-oxoadipate + NAD(+) = maleylacetate + NADH + H(+).

maleylacetoacetate isomerase (EC 5.2.1.2)

maleylacetoacetate isomerase. EC 5.2.1.2.. 4-maleylacetoacetate = 4-fumarylacetoacetate.

maleylpyruvate hydrolase (EC 3.7.1.23)

maleylpyruvate hydrolase. EC 3.7.1.23.. 3-maleylpyruvate + H2O = maleate + pyruvate + H(+).

maleylpyruvate isomerase (EC 5.2.1.4)

maleylpyruvate isomerase. EC 5.2.1.4.. 3-maleylpyruvate = 3-fumarylpyruvate.

malolactic enzyme (EC 4.1.1.101)

malolactic enzyme. EC 4.1.1.101.. (S)-malate + H(+) = (S)-lactate + CO2.

malonate CoA-transferase (EC 2.8.3.3)

malonate CoA-transferase. EC 2.8.3.3.. malonate + acetyl-CoA = acetate + malonyl-CoA.

malonate decarboxylase holo-[acyl-carrier protein] synthase (EC 2.7.7.66)

malonate decarboxylase holo-[acyl-carrier protein] synthase. EC 2.7.7.66.. apo-[malonate decarboxylase ACP] + 2'-(5''-triphospho-alpha-D-ribosyl)-

malonate--CoA ligase (EC 6.2.1.76)

malonate--CoA ligase. EC 6.2.1.76.. malonate + ATP + CoA = malonyl-CoA + AMP + diphosphate.

malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18)

malonate-semialdehyde dehydrogenase (acetylating). EC 1.2.1.18.. (1) 3-oxopropanoate + NADP(+) + CoA = acetyl-CoA + CO2 + NADPH.

malonate-semialdehyde dehydrogenase (EC 1.2.1.15)

malonate-semialdehyde dehydrogenase. EC 1.2.1.15.. (1) 3-oxopropanoate + NADP(+) + H2O = malonate + NADPH + 2 H(+).

malonyl CoA reductase (malonate semialdehyde-forming) (EC 1.2.1.75)

malonyl CoA reductase (malonate semialdehyde-forming). EC 1.2.1.75.. 3-oxopropanoate + NADP(+) + CoA = malonyl-CoA + NADPH + H(+).

malonyl-[acp] decarboxylase (EC 4.1.1.124)

malonyl-[acp] decarboxylase. EC 4.1.1.124.. malonyl-[ACP] + H(+) = acetyl-[ACP] + CO2.

malonyl-[acyl-carrier protein] O-methyltransferase (EC 2.1.1.197)

malonyl-[acyl-carrier protein] O-methyltransferase. EC 2.1.1.197.. malonyl-[ACP] + S-adenosyl-L-methionine = malonyl-[ACP] methyl ester +

malonyl-[malonate decarboxylase] decarboxylase (EC 4.1.1.87)

malonyl-[malonate decarboxylase] decarboxylase. EC 4.1.1.87.. malonyl-[ACP] + H(+) = acetyl-[ACP] + CO2.

malonyl-CoA decarboxylase (EC 4.1.1.9)

malonyl-CoA decarboxylase. EC 4.1.1.9.. malonyl-CoA + H(+) = acetyl-CoA + CO2.

malonyl-S-ACP:biotin-protein carboxyltransferase (EC 2.1.3.10)

malonyl-S-ACP:biotin-protein carboxyltransferase. EC 2.1.3.10.. N(6)-biotinyl-L-lysyl-[protein] + malonyl-[ACP] = N(6)-carboxybiotinyl-L-

maltokinase (EC 2.7.1.175)

maltokinase. EC 2.7.1.175.. D-maltose + ATP = alpha-maltose 1-phosphate + ADP + H(+).

maltose 6'-phosphate phosphatase (EC 3.1.3.90)

maltose 6'-phosphate phosphatase. EC 3.1.3.90.. alpha-maltose 6'-phosphate + H2O = D-maltose + phosphate.

maltose alpha-D-glucosyltransferase (EC 5.4.99.16)

maltose alpha-D-glucosyltransferase. EC 5.4.99.16.. D-maltose = alpha,alpha-trehalose.

maltose epimerase (EC 5.1.3.21)

maltose epimerase. EC 5.1.3.21.. alpha-maltose = beta-maltose.

maltose O-acetyltransferase (EC 2.3.1.79)

maltose O-acetyltransferase. EC 2.3.1.79.. D-maltose + acetyl-CoA = 1-O-acetylmaltose + CoA.

maltose phosphorylase (EC 2.4.1.8)

maltose phosphorylase. EC 2.4.1.8.. D-maltose + phosphate = beta-D-glucose 1-phosphate + D-glucose.

maltose synthase (EC 2.4.1.139)

maltose synthase. EC 2.4.1.139.. 2 alpha-D-glucose 1-phosphate + H2O = D-maltose + 2 phosphate.

maltose-6'-phosphate glucosidase (EC 3.2.1.122)

maltose-6'-phosphate glucosidase. EC 3.2.1.122.. alpha-maltose 6'-phosphate + H2O = D-glucose 6-phosphate + D-glucose.

malyl-CoA lyase (EC 4.1.3.24)

malyl-CoA lyase. EC 4.1.3.24.. (1) (S)-malyl-CoA = glyoxylate + acetyl-CoA.

mandelamide amidase (EC 3.5.1.86)

mandelamide amidase. EC 3.5.1.86.. (R)-mandelamide + H2O = (R)-mandelate + NH4(+).

mandelate 4-monooxygenase (EC 1.14.16.6)

mandelate 4-monooxygenase. EC 1.14.16.6.. (S)-mandelate + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + O2 = (S)-4-

mandelate racemase (EC 5.1.2.2)

mandelate racemase. EC 5.1.2.2.. (S)-mandelate = (R)-mandelate.