Enzymes A-Z
Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.
Enzymes A-Z
Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.
GTP 3',8-cyclase (EC 4.1.99.22)
GTP 3',8-cyclase. EC 4.1.99.22.. GTP + AH2 + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-
GTP cyclohydrolase I (EC 3.5.4.16)
GTP cyclohydrolase I. EC 3.5.4.16.. GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+).
GTP cyclohydrolase II (EC 3.5.4.25)
GTP cyclohydrolase II. EC 3.5.4.25.. GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine
GTP cyclohydrolase IIa (EC 3.5.4.29)
GTP cyclohydrolase IIa. EC 3.5.4.29.. GTP + 3 H2O = 2-amino-5-formylamino-6-(5-phospho-D-
GTP cyclohydrolase IV (EC 3.5.4.39)
GTP cyclohydrolase IV. EC 3.5.4.39.. GTP + H2O = 7,8-dihydroneopterin 2',3'-cyclic phosphate + formate +
GTP diphosphokinase (EC 2.7.6.5)
GTP diphosphokinase. EC 2.7.6.5.. GTP + ATP = guanosine 3'-diphosphate 5'-triphosphate + AMP.
GTP-dependent dephospho-CoA kinase (EC 2.7.1.237)
GTP-dependent dephospho-CoA kinase. EC 2.7.1.237.. 3'-dephospho-CoA + GTP = GDP + CoA + H(+).
guaia-4,6-diene synthase (EC 4.2.3.179)
guaia-4,6-diene synthase. EC 4.2.3.179.. (2E,6E)-farnesyl diphosphate = guaia-4,6-diene + diphosphate.
guanidinoacetase (EC 3.5.3.2)
guanidinoacetase. EC 3.5.3.2.. guanidinoacetate + H2O = urea + glycine.
guanidinoacetate kinase (EC 2.7.3.1)
guanidinoacetate kinase. EC 2.7.3.1.. guanidinoacetate + ATP = phosphoguanidinoacetate + ADP + H(+).
guanidinoacetate N-methyltransferase (EC 2.1.1.2)
guanidinoacetate N-methyltransferase. EC 2.1.1.2.. guanidinoacetate + S-adenosyl-L-methionine = creatine + S-adenosyl-L-
guanidinobutyrase (EC 3.5.3.7)
guanidinobutyrase. EC 3.5.3.7.. 4-guanidinobutanoate + H2O = urea + 4-aminobutanoate.
guanidinodeoxy-scyllo-inositol-4-phosphatase (EC 3.1.3.40)
guanidinodeoxy-scyllo-inositol-4-phosphatase. EC 3.1.3.40.. 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O = 1-guanidino-1-
guanidinopropionase (EC 3.5.3.17)
guanidinopropionase. EC 3.5.3.17.. 3-guanidinopropanoate + H2O = urea + beta-alanine.
guanine deaminase (EC 3.5.4.3)
guanine deaminase. EC 3.5.4.3.. guanine + H2O + H(+) = xanthine + NH4(+).
guanine phosphate-protein transferase (EC 2.7.7.n6)
guanine phosphate-protein transferase. EC 2.7.7.n6.. L-tyrosyl-[protein] + GTP = O-(5'-guanylyl)-L-tyrosyl-[protein] +
guanosine deaminase (EC 3.5.4.15)
guanosine deaminase. EC 3.5.4.15.. guanosine + H2O + H(+) = xanthosine + NH4(+).
guanosine phosphorylase (EC 2.4.2.15)
guanosine phosphorylase. EC 2.4.2.15.. guanosine + phosphate = alpha-D-ribose 1-phosphate + guanine.
guanosine-3',5'-bis(diphosphate) 3'-diphosphatase (EC 3.1.7.2)
guanosine-3',5'-bis(diphosphate) 3'-diphosphatase. EC 3.1.7.2.. guanosine 3',5'-bis(diphosphate) + H2O = GDP + diphosphate + H(+).
guanosine-5'-diphospho-5'-[DNA] diphosphatase (EC 3.6.1.70)
guanosine-5'-diphospho-5'-[DNA] diphosphatase. EC 3.6.1.70.. a 5'-end guanosine-5'-diphospho-5'-(2'-deoxyribonucleoside)-DNA + H2O =
guanosine-5'-triphosphate,3'-diphosphate diphosphatase (EC 3.6.1.40)
guanosine-5'-triphosphate,3'-diphosphate diphosphatase. EC 3.6.1.40.. guanosine 3'-diphosphate 5'-triphosphate + H2O = guanosine
guanosine-diphosphatase (EC 3.6.1.42)
guanosine-diphosphatase. EC 3.6.1.42.. GDP + H2O = GMP + phosphate + H(+).
guanosine-triphosphate guanylyltransferase (EC 2.7.7.45)
guanosine-triphosphate guanylyltransferase. EC 2.7.7.45.. 2 GTP + H(+) = P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate.
guanylate cyclase (EC 4.6.1.2)
guanylate cyclase. EC 4.6.1.2.. GTP = 3',5'-cyclic GMP + diphosphate.
guanylate kinase (EC 2.7.4.8)
guanylate kinase. EC 2.7.4.8.. GMP + ATP = GDP + ADP.
guanylylpyridinol adelylase (EC 2.7.7.110)
guanylylpyridinol adelylase. EC 2.7.7.110.. guanylylpyridinol + ATP + H(+) = guanylylpyridinol-AMP + diphosphate.
guluronate-specific alginate lyase (EC 4.2.2.11)
guluronate-specific alginate lyase. EC 4.2.2.11.. Eliminative cleavage of alginate to give oligosaccharides with 4-deoxy-
H(+)-exporting diphosphatase (EC 7.1.3.1)
H(+)-exporting diphosphatase. EC 7.1.3.1.. diphosphate + H2O + H(+)(in) = 2 phosphate + 2 H(+)(out).
H(+)-transporting two-sector ATPase (EC 7.1.2.2)
H(+)-transporting two-sector ATPase. EC 7.1.2.2.. ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out).
H(+)/K(+)-exchanging ATPase (EC 7.2.2.19)
H(+)/K(+)-exchanging ATPase. EC 7.2.2.19.. K(+)(out) + ATP + H2O + H(+)(in) = K(+)(in) + ADP + phosphate +
H2:CoB-CoM heterodisulfide,ferredoxin reductase (EC 1.8.98.5)
H2:CoB-CoM heterodisulfide,ferredoxin reductase. EC 1.8.98.5.. coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+) =
halimadienyl-diphosphate synthase (EC 5.5.1.16)
halimadienyl-diphosphate synthase. EC 5.5.1.16.. geranylgeranyl diphosphate = tuberculosinyl diphosphate.
haloacetate dehalogenase (EC 3.8.1.3)
haloacetate dehalogenase. EC 3.8.1.3.. a haloacetate + H2O = a halide anion + glycolate + H(+).
haloalkane dehalogenase (EC 3.8.1.5)
haloalkane dehalogenase. EC 3.8.1.5.. 1-haloalkane + H2O = a halide anion + a primary alcohol + H(+).
hamamelose kinase (EC 2.7.1.102)
hamamelose kinase. EC 2.7.1.102.. D-hamamelose + ATP = D-hamamelose 2'-phosphate + ADP + H(+).
hapalindole G dimethylallyltransferase (EC 2.5.1.159)
hapalindole G dimethylallyltransferase. EC 2.5.1.159.. (1) hapalindole G + dimethylallyl diphosphate = ambiguine A +
hapalindole H synthase (EC 5.5.1.31)
hapalindole H synthase. EC 5.5.1.31.. 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole = hapalindole H.
hapalindole U synthase (EC 5.5.1.36)
hapalindole U synthase. EC 5.5.1.36.. 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole = hapalindole U.
hapalindole-type alkaloid chlorinase (EC 1.14.20.14)
hapalindole-type alkaloid chlorinase. EC 1.14.20.14.. (1) hapalindole U + chloride + 2-oxoglutarate + O2 + H(+) = hapalindole G
HECT-type E3 ubiquitin transferase (EC 2.3.2.26)
HECT-type E3 ubiquitin transferase. EC 2.3.2.26.. S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor
helper-component proteinase (EC 3.4.22.45)
helper-component proteinase. EC 3.4.22.45.. Hydrolyzes a Gly-|-Gly bond at its own C-terminus, commonly in the
heme a synthase (EC 1.17.99.9)
heme a synthase. EC 1.17.99.9.. Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2.
heme ligase (EC 4.99.1.8)
heme ligase. EC 4.99.1.8.. 2 Fe(III)-heme b = beta-hematin.
heme o synthase (EC 2.5.1.141)
heme o synthase. EC 2.5.1.141.. heme b + (2E,6E)-farnesyl diphosphate + H2O = Fe(II)-heme o +
heme oxygenase (biliverdin-IX-beta and delta-forming) (EC 1.14.99.58)
heme oxygenase (biliverdin-IX-beta and delta-forming). EC 1.14.99.58.. (1) heme b + 3 AH2 + 3 O2 + 3 H(+) = biliverdin IXdelta + CO + Fe(2+) +
heme oxygenase (biliverdin-producing, ferredoxin) (EC 1.14.15.20)
heme oxygenase (biliverdin-producing, ferredoxin). EC 1.14.15.20.. heme b + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 8 H(+) = biliverdin
heme oxygenase (biliverdin-producing) (EC 1.14.14.18)
heme oxygenase (biliverdin-producing). EC 1.14.14.18.. heme b + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = biliverdin
heme oxygenase (mycobilin-producing) (EC 1.14.99.57)
heme oxygenase (mycobilin-producing). EC 1.14.99.57.. (1) heme b + 3 AH2 + 3 O2 + 2 H(+) = mycobilin a + Fe(2+) + 3 A + 3 H2O.
heme oxygenase (staphylobilin-producing) (EC 1.14.99.48)
heme oxygenase (staphylobilin-producing). EC 1.14.99.48.. (1) heme b + 5 AH2 + 4 O2 + 2 H(+) = delta-staphylobilin + Fe(2+) +
hepacivirin (EC 3.4.21.98)
hepacivirin. EC 3.4.21.98.. Hydrolysis of four peptide bonds in the viral precursor polyprotein,
heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78)
heparan-alpha-glucosaminide N-acetyltransferase. EC 2.3.1.78.. alpha-D-glucosaminyl-[heparan sulfate](n) + acetyl-CoA = N-acetyl-alpha-
heparanase (EC 3.2.1.166)
heparanase. EC 3.2.1.166.. endohydrolysis of (1->4)-beta-D-glycosidic bonds of heparan sulfate
heparin lyase (EC 4.2.2.7)
heparin lyase. EC 4.2.2.7.. Eliminative cleavage of polysaccharides containing (1->4)-linked
heparin-sulfate lyase (EC 4.2.2.8)
heparin-sulfate lyase. EC 4.2.2.8.. Elimination of sulfate, appears to act on linkages between N-acetyl-D-
heparosan-glucuronate 5-epimerase (EC 5.1.3.36)
heparosan-glucuronate 5-epimerase. EC 5.1.3.36.. [heparosan](n) = [acharan](n).
heparosan-N-sulfate-glucuronate 5-epimerase (EC 5.1.3.17)
heparosan-N-sulfate-glucuronate 5-epimerase. EC 5.1.3.17.. [heparosan-N-sulfate](n) = [heparan-N-sulfate](n).
hepoxilin-epoxide hydrolase (EC 3.3.2.7)
hepoxilin-epoxide hydrolase. EC 3.3.2.7.. (5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate +
hepsin (EC 3.4.21.106)
hepsin. EC 3.4.21.106.. Cleavage after basic amino-acid residues, with Arg strongly preferred to
heptaprenyl diphosphate synthase (EC 2.5.1.30)
heptaprenyl diphosphate synthase. EC 2.5.1.30.. 4 isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = all-trans-
heptaprenylglyceryl phosphate synthase (EC 2.5.1.n9)
heptaprenylglyceryl phosphate synthase. EC 2.5.1.n9.. sn-glycerol 1-phosphate + all-trans-heptaprenyl diphosphate =