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Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

[histone H3]-lysine(9) N-dimethyltransferase (EC 2.1.1.368)

[histone H3]-lysine(9) N-dimethyltransferase. EC 2.1.1.368.. L-lysyl(9)-[histone H3] + 2 S-adenosyl-L-methionine = N(6),N(6)-dimethyl-

[histone H3]-lysine(9) N-methyltransferase (EC 2.1.1.367)

[histone H3]-lysine(9) N-methyltransferase. EC 2.1.1.367.. L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-

[histone H3]-lysine(9) N-trimethyltransferase (EC 2.1.1.355)

[histone H3]-lysine(9) N-trimethyltransferase. EC 2.1.1.355.. L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-

[histone H3]-N(6),N(6)-dimethyl-lysine(9) N-methyltransferase (EC 2.1.1.366)

[histone H3]-N(6),N(6)-dimethyl-lysine(9) N-methyltransferase. EC 2.1.1.366.. N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine =

[histone H3]-trimethyl-L-lysine(27) demethylase (EC 1.14.11.68)

[histone H3]-trimethyl-L-lysine(27) demethylase. EC 1.14.11.68.. N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 2-oxoglutarate +

[histone H3]-trimethyl-L-lysine(36) demethylase (EC 1.14.11.69)

[histone H3]-trimethyl-L-lysine(36) demethylase. EC 1.14.11.69.. N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate +

[histone H3]-trimethyl-L-lysine(4) demethylase (EC 1.14.11.67)

[histone H3]-trimethyl-L-lysine(4) demethylase. EC 1.14.11.67.. N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 2-oxoglutarate +

[histone H3]-trimethyl-L-lysine(9) demethylase (EC 1.14.11.66)

[histone H3]-trimethyl-L-lysine(9) demethylase. EC 1.14.11.66.. N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate +

[histone H4]-lysine(20) N-methyltransferase (EC 2.1.1.361)

[histone H4]-lysine(20) N-methyltransferase. EC 2.1.1.361.. L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-

[histone H4]-lysine(20) N-trimethyltransferase (EC 2.1.1.372)

[histone H4]-lysine(20) N-trimethyltransferase. EC 2.1.1.372.. L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-

[histone H4]-N-methyl-L-lysine(20) N-methyltransferase (EC 2.1.1.362)

[histone H4]-N-methyl-L-lysine(20) N-methyltransferase. EC 2.1.1.362.. N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine =

[histone-H3]-N(6),N(6)-dimethyl-L-lysine(4) FAD-dependent demethylase (EC 1.14.99.66)

[histone-H3]-N(6),N(6)-dimethyl-L-lysine(4) FAD-dependent demethylase. EC 1.14.99.66.. N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2 A + 2 H2O = L-lysyl(4)-

[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase (EC 2.7.11.31)

[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase. EC 2.7.11.31.. L-seryl-[3-hydroxy-3-methylglutaryl-coenzyme A reductase] + ATP =

[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase (EC 3.1.3.47)

[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase. EC 3.1.3.47.. [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O =

[isocitrate dehydrogenase (NADP(+))] kinase (EC 2.7.11.5)

[isocitrate dehydrogenase (NADP(+))] kinase. EC 2.7.11.5.. L-seryl-[isocitrate dehydrogenase] + ATP = O-phospho-L-seryl-[isocitrate

[low-density-lipoprotein receptor] kinase (EC 2.7.11.29)

[low-density-lipoprotein receptor] kinase. EC 2.7.11.29.. L-seryl-[low-density-lipoprotein receptor] + ATP = O-phospho-L-seryl-

[methionine synthase] reductase (EC 1.16.1.8)

[methionine synthase] reductase. EC 1.16.1.8.. 2 methylcob(III)alamin-[methionine synthase] + 2 S-adenosyl-L-

[methyl coenzyme M reductase]-L-arginine C-5-methyltransferase (EC 2.1.1.379)

[methyl coenzyme M reductase]-L-arginine C-5-methyltransferase. EC 2.1.1.379.. L-arginyl-[methyl-coenzyme M reductase] + AH2 + 2 S-adenosyl-L-methionine

[methyl-Co(III) glycine betaine-specific corrinoid protein]- (EC 2.1.1.378)

[methyl-Co(III) glycine betaine-specific corrinoid protein]-. EC 2.1.1.378.. methyl-Co(III)-[glycine betaine-specific corrinoid protein] + (6S)-

[methyl-Co(III) glycine betaine-specific corrinoid protein]--coenzyme M (EC 2.1.1.377)

[methyl-Co(III) glycine betaine-specific corrinoid protein]--coenzyme M. EC 2.1.1.377.. methyl-Co(III)-[glycine betaine-specific corrinoid protein] + coenzyme M

[methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M (EC 2.1.1.246)

[methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M. EC 2.1.1.246.. methyl-Co(III)-[methanol-specific corrinoid protein] + coenzyme M =

[methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid (EC 2.1.1.384)

[methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid. EC 2.1.1.384.. 5,6,7,8-tetrahydromethanopterin + methyl-Co(III)-[methoxylated-aromatic-

[methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid (EC 2.1.1.385)

[methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid. EC 2.1.1.385.. methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid

[methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M (EC 2.1.1.247)

[methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M. EC 2.1.1.247.. methyl-Co(III)-[methylamine-specific corrinoid protein] + coenzyme M =

[methyl-Co(III) quaternary-amine-specific corrinoid protein]- (EC 2.1.1.389)

[methyl-Co(III) quaternary-amine-specific corrinoid protein]-. EC 2.1.1.389.. methyl-Co(III)-[quaternary-amine-specific corrinoid protein] + (6S)-

[methyl-Co(III) tetramethylammonium-specific corrinoid protein]:coenzyme (EC 2.1.1.253)

[methyl-Co(III) tetramethylammonium-specific corrinoid protein]:coenzyme. EC 2.1.1.253.. methyl-Co(III)-[tetramethylammonium-specific corrinoid protein] +

[methylamine--corrinoid protein] Co-methyltransferase (EC 2.1.1.248)

[methylamine--corrinoid protein] Co-methyltransferase. EC 2.1.1.248.. Co(I)-[methylamine-specific corrinoid protein] + methylamine + H(+) =

[mycofactocin precursor peptide] peptidase (EC 3.4.14.14)

[mycofactocin precursor peptide] peptidase. EC 3.4.14.14.. [mycofactocin precursor peptide]-C-terminal glycyl-N-

[mycofactocin precursor peptide]-tyrosine decarboxylase (EC 1.3.98.7)

[mycofactocin precursor peptide]-tyrosine decarboxylase. EC 1.3.98.7.. [mycofactocin precursor peptide]-C-terminal glycyl-L-valyl-L-tyrosine +

[myelin-proteolipid] O-palmitoyltransferase (EC 2.3.1.100)

[myelin-proteolipid] O-palmitoyltransferase. EC 2.3.1.100.. L-cysteinyl-[myelin proteolipid protein] + hexadecanoyl-CoA =

[myosin heavy-chain] kinase (EC 2.7.11.7)

[myosin heavy-chain] kinase. EC 2.7.11.7.. L-threonyl-[myosin heavy-chain] + ATP = O-phospho-L-threonyl-[myosin

[myosin light-chain] kinase (EC 2.7.11.18)

[myosin light-chain] kinase. EC 2.7.11.18.. (1) L-seryl-[myosin light chain] + ATP = O-phospho-L-seryl-[myosin light

[myosin-light-chain] phosphatase (EC 3.1.3.53)

[myosin-light-chain] phosphatase. EC 3.1.3.53.. (1) O-phospho-L-seryl-[myosin light chain] + H2O = L-seryl-[myosin light

[phosphatase 2A protein]-leucine-carboxy methyltransferase (EC 2.1.1.233)

[phosphatase 2A protein]-leucine-carboxy methyltransferase. EC 2.1.1.233.. [phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine =

[phosphorylase] phosphatase (EC 3.1.3.17)

[phosphorylase] phosphatase. EC 3.1.3.17.. [phosphorylase a] + 4 H2O = 2 [phosphorylase b] + 4 phosphate.

[protein ADP-ribosylarginine] hydrolase (EC 3.2.2.19)

[protein ADP-ribosylarginine] hydrolase. EC 3.2.2.19.. (1) N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + H2O = ADP-D-ribose +

[protein-PII] uridylyltransferase (EC 2.7.7.59)

[protein-PII] uridylyltransferase. EC 2.7.7.59.. [protein-PII]-L-tyrosine + UTP = [protein-PII]-uridylyl-L-tyrosine +

[protein]-arginine 3-hydroxylase (EC 1.14.11.73)

[protein]-arginine 3-hydroxylase. EC 1.14.11.73.. L-arginyl-[protein] + 2-oxoglutarate + O2 = (3R)-3-hydroxy-L-arginyl-

[pyruvate dehydrogenase (acetyl-transferring)] kinase (EC 2.7.11.2)

[pyruvate dehydrogenase (acetyl-transferring)] kinase. EC 2.7.11.2.. L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ATP = O-phospho-L-

[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase (EC 3.1.3.43)

[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase. EC 3.1.3.43.. O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + H2O =

[pyruvate kinase]-phosphatase (EC 3.1.3.49)

[pyruvate kinase]-phosphatase. EC 3.1.3.49.. [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate.

[pyruvate, phosphate dikinase] kinase (EC 2.7.11.32)

[pyruvate, phosphate dikinase] kinase. EC 2.7.11.32.. N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] +

[pyruvate, water dikinase] kinase (EC 2.7.11.33)

[pyruvate, water dikinase] kinase. EC 2.7.11.33.. [pyruvate, water dikinase] + ADP = [pyruvate, water dikinase]-phosphate +

[ribosomal protein bS18]-alanine N-acetyltransferase (EC 2.3.1.266)

[ribosomal protein bS18]-alanine N-acetyltransferase. EC 2.3.1.266.. N-terminal L-alanyl-[ribosomal protein bS18] + acetyl-CoA = N-terminal

[ribosomal protein uS12] (aspartate(89)-C(3))-methylthiotransferase (EC 2.8.4.4)

[ribosomal protein uS12] (aspartate(89)-C(3))-methylthiotransferase. EC 2.8.4.4.. L-aspartate(89)-[ribosomal protein uS12]-hydrogen + (sulfur carrier)-SH +

[ribosomal protein uS5]-alanine N-acetyltransferase (EC 2.3.1.267)

[ribosomal protein uS5]-alanine N-acetyltransferase. EC 2.3.1.267.. N-terminal L-alanyl-[ribosomal protein uS5] + acetyl-CoA = N-terminal

[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase (EC 2.1.1.127)

[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase. EC 2.1.1.127.. L-lysyl-[ribulose-1,5-bisphosphate carboxylase] + 3 S-adenosyl-L-

[RNA-polymerase]-subunit kinase (EC 2.7.11.23)

[RNA-polymerase]-subunit kinase. EC 2.7.11.23.. [DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA

[Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase (EC 2.4.1.229)

[Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase. EC 2.4.1.229.. trans-4-hydroxy-L-prolyl-[Skp1 protein] + UDP-N-acetyl-alpha-D-

[Src-family] C-terminal protein kinase (EC 2.7.10.4)

[Src-family] C-terminal protein kinase. EC 2.7.10.4.. ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-

[tau protein] kinase (EC 2.7.11.26)

[tau protein] kinase. EC 2.7.11.26.. (1) L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP +

[trehalose-6-phosphate synthase]-L-cysteine S-methyltransferase (EC 2.1.1.318)

[trehalose-6-phosphate synthase]-L-cysteine S-methyltransferase. EC 2.1.1.318.. [trehalose-6-phosphate synthase]-L-cysteine + S-adenosyl-L-methionine =

[trimethylamine--corrinoid protein] Co-methyltransferase (EC 2.1.1.250)

[trimethylamine--corrinoid protein] Co-methyltransferase. EC 2.1.1.250.. Co(I)-[trimethylamine-specific corrinoid protein] + trimethylamine + H(+)

[tyrosine 3-monooxygenase] kinase (EC 2.7.11.6)

[tyrosine 3-monooxygenase] kinase. EC 2.7.11.6.. L-seryl-[tyrosine-3-monooxygenase] + ATP = O-phospho-L-seryl-[tyrosine-3-

[Wnt protein] O-palmitoleoyl transferase (EC 2.3.1.250)

[Wnt protein] O-palmitoleoyl transferase. EC 2.3.1.250.. [Wnt protein]-L-serine + (9Z)-hexadecenoyl-CoA = [Wnt protein]-O-(9Z)-

[Wnt protein] O-palmitoleoyl-L-serine hydrolase (EC 3.1.1.98)

[Wnt protein] O-palmitoleoyl-L-serine hydrolase. EC 3.1.1.98.. [Wnt protein]-O-(9Z)-hexadecenoyl-L-serine + H2O = [Wnt protein]-L-serine

1-(5-phosphoribosyl)-5- (EC 5.3.1.16)

1-(5-phosphoribosyl)-5-. EC 5.3.1.16.. 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-

1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.n4)

1-acyl-sn-glycerol-3-phosphate acyltransferase. EC 2.3.1.n4.. a fatty acyl-[ACP] + a 1-acyl-sn-glycero-3-phosphate = a 1,2-diacyl-

1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51)

1-acylglycerol-3-phosphate O-acyltransferase. EC 2.3.1.51.. a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-

1-acylglycerophosphocholine O-acyltransferase (EC 2.3.1.23)

1-acylglycerophosphocholine O-acyltransferase. EC 2.3.1.23.. a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-