Enzymes A-Z
Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.
Enzymes A-Z
Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.
cobaltochelatase (EC 6.6.1.2)
cobaltochelatase. EC 6.6.1.2.. hydrogenobyrinate a,c-diamide + Co(2+) + ATP + H2O = cob(II)yrinate a,c
cobyrinate a,c-diamide synthase (glutamine-hydrolyzing) (EC 6.3.5.11)
cobyrinate a,c-diamide synthase (glutamine-hydrolyzing). EC 6.3.5.11.. cob(II)yrinate + 2 L-glutamine + 2 ATP + 2 H2O = cob(II)yrinate a,c
cocaine esterase (EC 3.1.1.84)
cocaine esterase. EC 3.1.1.84.. cocaine + H2O = ecgonine methyl ester + benzoate + H(+).
cocaine synthase (EC 2.3.1.334)
cocaine synthase. EC 2.3.1.334.. ecgonine methyl ester + benzoyl-CoA = cocaine + CoA.
coccolysin (EC 3.4.24.30)
coccolysin. EC 3.4.24.30.. Preferential cleavage: Xaa-|-Leu, Xaa-|-Phe, Xaa-|-Tyr, Xaa-|-Ala.
codeine 3-O-demethylase (EC 1.14.11.32)
codeine 3-O-demethylase. EC 1.14.11.32.. codeine + 2-oxoglutarate + O2 = morphine + formaldehyde + succinate +
codeinone reductase (NADPH) (EC 1.1.1.247)
codeinone reductase (NADPH). EC 1.1.1.247.. codeine + NADP(+) = codeinone + NADPH + H(+).
coelimycin P1 polyketide synthase (EC 2.3.1.281)
coelimycin P1 polyketide synthase. EC 2.3.1.281.. 6 malonyl-CoA + NADH + 5 NADPH + 12 H(+) = (2E,5S,6E,8E,10E)-5-
coenzyme A diphosphatase (EC 3.6.1.77)
coenzyme A diphosphatase. EC 3.6.1.77.. CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate +
coenzyme F420 hydrogenase (EC 1.12.98.1)
coenzyme F420 hydrogenase. EC 1.12.98.1.. oxidized coenzyme F420-(gamma-L-Glu)(n) + H2 + H(+) = reduced coenzyme
coenzyme F420 oxidoreductase (ferredoxin) (EC 1.5.7.2)
coenzyme F420 oxidoreductase (ferredoxin). EC 1.5.7.2.. reduced coenzyme F420-(gamma-L-Glu)(n) + 2 oxidized [2Fe-2S]-[ferredoxin]
coenzyme F420-0:L-glutamate ligase (EC 6.3.2.31)
coenzyme F420-0:L-glutamate ligase. EC 6.3.2.31.. oxidized coenzyme F420-0 + GTP + L-glutamate = oxidized coenzyme F420-1 +
coenzyme F420-1:gamma-L-glutamate ligase (EC 6.3.2.34)
coenzyme F420-1:gamma-L-glutamate ligase. EC 6.3.2.34.. oxidized coenzyme F420-1 + GTP + L-glutamate = oxidized coenzyme F420-2 +
coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase (EC 1.8.98.4)
coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase. EC 1.8.98.4.. coenzyme B + 2 oxidized coenzyme F420-(gamma-L-Glu)(n) + coenzyme M +
coenzyme F420:methanophenazine dehydrogenase (EC 1.5.98.3)
coenzyme F420:methanophenazine dehydrogenase. EC 1.5.98.3.. methanophenazine + reduced coenzyme F420-(gamma-L-Glu)(n) =
coenzyme F420H2 oxidase (EC 1.5.3.22)
coenzyme F420H2 oxidase. EC 1.5.3.22.. 2 reduced coenzyme F420-(gamma-L-Glu)(n) + O2 = 2 oxidized coenzyme F420-
coenzyme F430 synthetase (EC 6.4.1.9)
coenzyme F430 synthetase. EC 6.4.1.9.. 15,17(3)-seco-F430-17(3)-acid + ATP = coenzyme F430 + ADP + phosphate.
coenzyme gamma-F420-2:alpha-L-glutamate ligase (EC 6.3.2.32)
coenzyme gamma-F420-2:alpha-L-glutamate ligase. EC 6.3.2.32.. oxidized coenzyme F420-2 + L-glutamate + ATP = oxidized coenzyme alpha-
coenzyme-B sulfoethylthiotransferase (EC 2.8.4.1)
coenzyme-B sulfoethylthiotransferase. EC 2.8.4.1.. coenzyme B + methyl-coenzyme M = methane + coenzyme M-coenzyme B
colleterpenol synthase (EC 4.2.3.213)
colleterpenol synthase. EC 4.2.3.213.. all-trans-hexaprenyl diphosphate + H2O = colleterpenol + diphosphate.
colneleate synthase (EC 4.2.1.121)
colneleate synthase. EC 4.2.1.121.. (9S)-hydroperoxy-(10E,12Z)-octadecadienoate = colneleate + H2O.
columbamine O-methyltransferase (EC 2.1.1.118)
columbamine O-methyltransferase. EC 2.1.1.118.. columbamine + S-adenosyl-L-methionine = palmatine + S-adenosyl-L-
columbamine oxidase (EC 1.21.3.2)
columbamine oxidase. EC 1.21.3.2.. 2 columbamine + O2 = 2 berberine + 2 H2O.
complement factor D (EC 3.4.21.46)
complement factor D. EC 3.4.21.46.. Selective cleavage of Arg-|-Lys bond in complement factor B when in
complement factor I (EC 3.4.21.45)
complement factor I. EC 3.4.21.45.. Inactivates complement subcomponents C3b, iC3b and C4b by proteolytic
complement subcomponent C1r (EC 3.4.21.41)
complement subcomponent C1r. EC 3.4.21.41.. Selective cleavage of Lys(or Arg)-|-Ile bond in complement subcomponent
complement subcomponent C1s (EC 3.4.21.42)
complement subcomponent C1s. EC 3.4.21.42.. Cleavage of Arg-|-Ala bond in complement component C4 to form C4a and
coniferin beta-glucosidase (EC 3.2.1.126)
coniferin beta-glucosidase. EC 3.2.1.126.. 4-O-(beta-D-glucosyl)-(E)-coniferol + H2O = (E)-coniferol + D-glucose.
coniferyl-alcohol dehydrogenase (EC 1.1.1.194)
coniferyl-alcohol dehydrogenase. EC 1.1.1.194.. (E)-coniferol + NADP(+) = (E)-coniferaldehyde + NADPH + H(+).
coniferyl-alcohol glucosyltransferase (EC 2.4.1.111)
coniferyl-alcohol glucosyltransferase. EC 2.4.1.111.. (E)-coniferol + UDP-alpha-D-glucose = 4-O-(beta-D-glucosyl)-(E)-coniferol
coniferyl-aldehyde dehydrogenase (EC 1.2.1.68)
coniferyl-aldehyde dehydrogenase. EC 1.2.1.68.. (1) (E)-coniferaldehyde + NADP(+) + H2O = (E)-ferulate + NADPH + 2 H(+).
copal-8-ol diphosphate hydratase (EC 4.2.1.133)
copal-8-ol diphosphate hydratase. EC 4.2.1.133.. (2E,6E,10E)-geranylgeranyl diphosphate + H2O = 8-hydroxycopalyl
copalyl diphosphate synthase (EC 5.5.1.12)
copalyl diphosphate synthase. EC 5.5.1.12.. (2E,6E,10E)-geranylgeranyl diphosphate = (+)-copalyl diphosphate.
coproporphyrin ferrochelatase (EC 4.99.1.9)
coproporphyrin ferrochelatase. EC 4.99.1.9.. Fe-coproporphyrin III + 2 H(+) = coproporphyrin III + Fe(2+).
coproporphyrinogen dehydrogenase (EC 1.3.98.3)
coproporphyrinogen dehydrogenase. EC 1.3.98.3.. coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen
coproporphyrinogen III oxidase (coproporphyrin-forming) (EC 1.3.3.15)
coproporphyrinogen III oxidase (coproporphyrin-forming). EC 1.3.3.15.. coproporphyrinogen III + 3 O2 = coproporphyrin III + 3 H2O2.
coproporphyrinogen oxidase (EC 1.3.3.3)
coproporphyrinogen oxidase. EC 1.3.3.3.. coproporphyrinogen III + O2 + 2 H(+) = protoporphyrinogen IX + 2 CO2 +
corrinoid adenosyltransferase (EC 2.5.1.17)
corrinoid adenosyltransferase. EC 2.5.1.17.. (1) 2 cob(II)alamin + reduced [electron-transfer flavoprotein] + 2 ATP =
corrinoid adenosyltransferase EutT (EC 2.5.1.154)
corrinoid adenosyltransferase EutT. EC 2.5.1.154.. 2 cob(II)alamin + reduced [electron-transfer flavoprotein] + 2 ATP +
corticosteroid side-chain-isomerase (EC 5.3.1.21)
corticosteroid side-chain-isomerase. EC 5.3.1.21.. 21-hydroxyprogesterone = 20-hydroxy-3-oxopregn-4-en-21-al.
corticosterone 18-monooxygenase (EC 1.14.15.5)
corticosterone 18-monooxygenase. EC 1.14.15.5.. corticosterone + 2 reduced [adrenodoxin] + O2 + 2 H(+) =
cortisol O-acetyltransferase (EC 2.3.1.27)
cortisol O-acetyltransferase. EC 2.3.1.27.. cortisol + acetyl-CoA = cortisol 21-acetate + CoA.
cortisol sulfotransferase (EC 2.8.2.18)
cortisol sulfotransferase. EC 2.8.2.18.. cortisol + 3'-phosphoadenylyl sulfate = cortisol 21-sulfate + adenosine
corydaline synthase (EC 2.1.1.147)
corydaline synthase. EC 2.1.1.147.. palmatine + S-adenosyl-L-methionine + 2 NADPH = corydaline + S-adenosyl-
costunolide synthase (EC 1.14.14.150)
costunolide synthase. EC 1.14.14.150.. germacra-1(10),4,11(13)-trien-12-oate + reduced [NADPH--hemoprotein
coumarin 8-geranyltransferase (EC 2.5.1.138)
coumarin 8-geranyltransferase. EC 2.5.1.138.. (1) umbelliferone + (2E)-geranyl diphosphate = 8-geranylumbelliferone +
creatinase (EC 3.5.3.3)
creatinase. EC 3.5.3.3.. creatine + H2O = sarcosine + urea.
creatine kinase (EC 2.7.3.2)
creatine kinase. EC 2.7.3.2.. creatine + ATP = N-phosphocreatine + ADP + H(+).
creatininase (EC 3.5.2.10)
creatininase. EC 3.5.2.10.. creatinine + H2O = creatine.
creatinine deaminase (EC 3.5.4.21)
creatinine deaminase. EC 3.5.4.21.. creatinine + H2O + H(+) = N-methylhydantoin + NH4(+).
CRIK-subfamily protein kinase (EC 2.7.11.35)
CRIK-subfamily protein kinase. EC 2.7.11.35.. (1) L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).
crocetin dialdehyde synthase (EC 1.13.11.84)
crocetin dialdehyde synthase. EC 1.13.11.84.. all-trans-zeaxanthin + 2 O2 = crocetin dialdehyde + 2 3beta-hydroxy-beta-
crocetin glucosyltransferase (EC 2.4.1.271)
crocetin glucosyltransferase. EC 2.4.1.271.. (1) crocetin + UDP-alpha-D-glucose = beta-D-glucosyl crocetin + UDP.
crossover junction endodeoxyribonuclease (EC 3.1.21.10)
crossover junction endodeoxyribonuclease. EC 3.1.21.10.. Endonucleolytic cleavage at a junction such as a reciprocal single-
crotonobetainyl-CoA hydratase (EC 4.2.1.149)
crotonobetainyl-CoA hydratase. EC 4.2.1.149.. (R)-carnitinyl-CoA = crotonobetainyl-CoA + H2O.
crotonobetainyl-CoA reductase (EC 1.3.8.13)
crotonobetainyl-CoA reductase. EC 1.3.8.13.. 4-(trimethylamino)butanoyl-CoA + oxidized [electron-transfer
crotonyl-CoA carboxylase/reductase (EC 1.3.1.85)
crotonyl-CoA carboxylase/reductase. EC 1.3.1.85.. (2S)-ethylmalonyl-CoA + NADP(+) = (2E)-butenoyl-CoA + CO2 + NADPH.
crotonyl-CoA reductase (EC 1.3.1.86)
crotonyl-CoA reductase. EC 1.3.1.86.. butanoyl-CoA + NADP(+) = (2E)-butenoyl-CoA + NADPH + H(+).
cruzipain (EC 3.4.22.51)
cruzipain. EC 3.4.22.51.. Broad endopeptidase specificity similar to that of cathepsin L.
CTP synthase (glutamine hydrolyzing) (EC 6.3.4.2)
CTP synthase (glutamine hydrolyzing). EC 6.3.4.2.. UTP + L-glutamine + ATP + H2O = CTP + L-glutamate + ADP + phosphate +