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Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

chymase (EC 3.4.21.39)

chymase. EC 3.4.21.39.. Preferential cleavage: Phe-|-Xaa > Tyr-|-Xaa > Trp-|-Xaa > Leu-|-Xaa.

chymopapain (EC 3.4.22.6)

chymopapain. EC 3.4.22.6.. Specificity similar to that of papain.

chymosin (EC 3.4.23.4)

chymosin. EC 3.4.23.4.. Broad specificity similar to that of pepsin A. Clots milk by cleavage of

chymotrypsin (EC 3.4.21.1)

chymotrypsin. EC 3.4.21.1.. Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.

chymotrypsin C (EC 3.4.21.2)

chymotrypsin C. EC 3.4.21.2.. Preferential cleavage: Leu-|-Xaa, Tyr-|-Xaa, Phe-|-Xaa, Met-|-Xaa,

cinnamate beta-D-glucosyltransferase (EC 2.4.1.177)

cinnamate beta-D-glucosyltransferase. EC 2.4.1.177.. (E)-cinnamate + UDP-alpha-D-glucose = 1-O-(trans-cinnamoyl)-beta-D-

cinnamoyl-CoA reductase (EC 1.2.1.44)

cinnamoyl-CoA reductase. EC 1.2.1.44.. (E)-cinnamaldehyde + NADP(+) + CoA = (E)-cinnamoyl-CoA + NADPH + H(+).

cinnamyl-alcohol dehydrogenase (EC 1.1.1.195)

cinnamyl-alcohol dehydrogenase. EC 1.1.1.195.. (E)-cinnamyl alcohol + NADP(+) = (E)-cinnamaldehyde + NADPH + H(+).

cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase (EC 1.3.1.29)

cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase. EC 1.3.1.29.. (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD(+) = naphthalene-1,2-diol +

cis-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.19)

cis-1,2-dihydrobenzene-1,2-diol dehydrogenase. EC 1.3.1.19.. cis-1,2-dihydrobenzene-1,2-diol + NAD(+) = catechol + NADH + H(+).

cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate (EC 1.3.1.67)

cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate. EC 1.3.1.67.. (1) (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate +

cis-2-enoyl-CoA reductase (NADPH) (EC 1.3.1.37)

cis-2-enoyl-CoA reductase (NADPH). EC 1.3.1.37.. acyl-CoA + NADP(+) = cis-2,3-dehydroacyl-CoA + NADPH + H(+).

cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC 1.3.1.56)

cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase. EC 1.3.1.56.. (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+) = biphenyl-2,3-diol

cis-3-alkyl-4-alkyloxetan-2-one decarboxylase (EC 4.1.1.114)

cis-3-alkyl-4-alkyloxetan-2-one decarboxylase. EC 4.1.1.114.. a cis-3-alkyl-4-alkyloxetan-2-one = a cis-alkene + CO2.

cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase (EC 1.3.1.49)

cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase. EC 1.3.1.49.. (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+) = phenanthrene-3,4-diol

cis-4-hydroxycyclohexanecarboxylate dehydrogenase (EC 1.1.1.438)

cis-4-hydroxycyclohexanecarboxylate dehydrogenase. EC 1.1.1.438.. cis-4-hydroxycyclohexane-1-carboxylate + NAD(+) = 4-oxocyclohexane-1-

cis-abienol synthase (EC 4.2.3.140)

cis-abienol synthase. EC 4.2.3.140.. 8-hydroxycopalyl diphosphate = cis-abienol + diphosphate.

cis-aconitate decarboxylase (EC 4.1.1.6)

cis-aconitate decarboxylase. EC 4.1.1.6.. cis-aconitate + H(+) = itaconate + CO2.

cis-dihydroethylcatechol dehydrogenase (EC 1.3.1.66)

cis-dihydroethylcatechol dehydrogenase. EC 1.3.1.66.. cis-1,2-dihydro-3-ethylcatechol + NAD(+) = 3-ethylcatechol + NADH + H(+).

cis-L-3-hydroxyproline dehydratase (EC 4.2.1.171)

cis-L-3-hydroxyproline dehydratase. EC 4.2.1.171.. cis-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O.

cis-muuroladiene synthase (EC 4.2.3.67)

cis-muuroladiene synthase. EC 4.2.3.67.. (1) (2E,6E)-farnesyl diphosphate = cis-muurola-3,5-diene + diphosphate.

cis-p-coumarate glucosyltransferase (EC 2.4.1.209)

cis-p-coumarate glucosyltransferase. EC 2.4.1.209.. cis-4-coumarate + UDP-alpha-D-glucose = 4'-O-beta-D-glucosyl-cis-4-

cis-zeatin O-beta-D-glucosyltransferase (EC 2.4.1.215)

cis-zeatin O-beta-D-glucosyltransferase. EC 2.4.1.215.. cis-zeatin + UDP-alpha-D-glucose = O-beta-D-glucosyl-cis-zeatin + UDP +

citramalate CoA-transferase (EC 2.8.3.11)

citramalate CoA-transferase. EC 2.8.3.11.. citramalate + acetyl-CoA = (3S)-citramalyl-CoA + acetate.

citramalate lyase (EC 4.1.3.22)

citramalate lyase. EC 4.1.3.22.. (3S)-citramalate = acetate + pyruvate.

citrate (pro-3S)-lyase (EC 4.1.3.6)

citrate (pro-3S)-lyase. EC 4.1.3.6.. citrate = oxaloacetate + acetate.

citrate (Re)-synthase (EC 2.3.3.3)

citrate (Re)-synthase. EC 2.3.3.3.. oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H(+).

citrate (Si)-synthase (EC 2.3.3.1)

citrate (Si)-synthase. EC 2.3.3.1.. oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H(+).

citrate CoA-transferase (EC 2.8.3.10)

citrate CoA-transferase. EC 2.8.3.10.. citrate + acetyl-CoA = (3S)-citryl-CoA + acetate.

citrate lyase holo-[acyl-carrier protein] synthase (EC 2.7.7.61)

citrate lyase holo-[acyl-carrier protein] synthase. EC 2.7.7.61.. apo-[citrate lyase ACP] + 2'-(5''-triphospho-alpha-D-ribosyl)-

citrate synthase (unknown stereospecificity) (EC 2.3.3.16)

citrate synthase (unknown stereospecificity). EC 2.3.3.16.. oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H(+).

citrate--CoA ligase (EC 6.2.1.18)

citrate--CoA ligase. EC 6.2.1.18.. citrate + ATP + CoA = (3S)-citryl-CoA + ADP + phosphate.

citrate-lyase deacetylase (EC 3.1.2.16)

citrate-lyase deacetylase. EC 3.1.2.16.. acetyl-[citrate lyase ACP] + H2O = holo-[citrate lyase ACP] + acetate +

citrullinase (EC 3.5.1.20)

citrullinase. EC 3.5.1.20.. L-citrulline + H2O + 2 H(+) = L-ornithine + NH4(+) + CO2.

citryl-CoA lyase (EC 4.1.3.34)

citryl-CoA lyase. EC 4.1.3.34.. (3S)-citryl-CoA = oxaloacetate + acetyl-CoA.

classical-complement-pathway C3/C5 convertase (EC 3.4.21.43)

classical-complement-pathway C3/C5 convertase. EC 3.4.21.43.. Selective cleavage of Arg-|-Ser bond in complement component C3 alpha-

clavaminate synthase (EC 1.14.11.21)

clavaminate synthase. EC 1.14.11.21.. (1) deoxyamidinoproclavaminate + 2-oxoglutarate + O2 =

clostridial aminopeptidase (EC 3.4.11.13)

clostridial aminopeptidase. EC 3.4.11.13.. Release of any N-terminal amino acid, including proline and

clostripain (EC 3.4.22.8)

clostripain. EC 3.4.22.8.. Preferential cleavage: Arg-|-Xaa, including Arg-|-Pro bond, but not

CMP-N-acetylneuraminate monooxygenase (EC 1.14.18.2)

CMP-N-acetylneuraminate monooxygenase. EC 1.14.18.2.. CMP-N-acetyl-beta-neuraminate + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) =

CMP-N-acylneuraminate phosphodiesterase (EC 3.1.4.40)

CMP-N-acylneuraminate phosphodiesterase. EC 3.1.4.40.. a CMP-N-acyl-beta-neuraminate + H2O = an N-acylneuraminate + CMP + H(+).

CMP-N,N'-diacetyllegionaminic acid synthase (EC 2.7.7.82)

CMP-N,N'-diacetyllegionaminic acid synthase. EC 2.7.7.82.. N,N-diacetyllegionaminate + CTP = CMP-N,N-diacetyllegionaminate +

CO-methylating acetyl-CoA synthase (EC 2.3.1.169)

CO-methylating acetyl-CoA synthase. EC 2.3.1.169.. Co(I)-[corrinoid Fe-S protein] + acetyl-CoA + H(+) = methyl-Co(III)-

CoA-disulfide reductase (EC 1.8.1.14)

CoA-disulfide reductase. EC 1.8.1.14.. NADP(+) + 2 CoA = CoA-disulfide + NADPH + H(+).

CoA-glutathione reductase (EC 1.8.1.10)

CoA-glutathione reductase. EC 1.8.1.10.. glutathione + NADP(+) + CoA = CoA-glutathione + NADPH + H(+).

CoA:oxalate CoA-transferase (EC 2.8.3.19)

CoA:oxalate CoA-transferase. EC 2.8.3.19.. oxalate + acetyl-CoA = oxalyl-CoA + acetate.

coagulation factor IXa (EC 3.4.21.22)

coagulation factor IXa. EC 3.4.21.22.. Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.

coagulation factor VIIa (EC 3.4.21.21)

coagulation factor VIIa. EC 3.4.21.21.. Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.

coagulation factor Xa (EC 3.4.21.6)

coagulation factor Xa. EC 3.4.21.6.. Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin

coagulation factor XIa (EC 3.4.21.27)

coagulation factor XIa. EC 3.4.21.27.. Selective cleavage of Arg-|-Ala and Arg-|-Val bonds in factor IX to form

coagulation factor XIIa (EC 3.4.21.38)

coagulation factor XIIa. EC 3.4.21.38.. Selective cleavage of Arg-|-Ile bonds in factor VII to form factor VIIa

cobalt-factor II C(20)-methyltransferase (EC 2.1.1.151)

cobalt-factor II C(20)-methyltransferase. EC 2.1.1.151.. Co-precorrin-2 + S-adenosyl-L-methionine = Co-precorrin-3 + S-adenosyl-L-

cobalt-factor III methyltransferase (EC 2.1.1.272)

cobalt-factor III methyltransferase. EC 2.1.1.272.. Co(II)-factor III + AH2 + S-adenosyl-L-methionine = Co-precorrin-4 + A +

cobalt-precorrin 5A hydrolase (EC 3.7.1.12)

cobalt-precorrin 5A hydrolase. EC 3.7.1.12.. Co-precorrin-5A + H2O = Co-precorrin-5B + acetaldehyde + H(+).

cobalt-precorrin-4 methyltransferase (EC 2.1.1.271)

cobalt-precorrin-4 methyltransferase. EC 2.1.1.271.. Co-precorrin-4 + S-adenosyl-L-methionine = Co-precorrin-5A + S-adenosyl-

cobalt-precorrin-5B (C(1))-methyltransferase (EC 2.1.1.195)

cobalt-precorrin-5B (C(1))-methyltransferase. EC 2.1.1.195.. Co-precorrin-5B + S-adenosyl-L-methionine = Co-precorrin-6A + S-adenosyl-

cobalt-precorrin-6A reductase (EC 1.3.1.106)

cobalt-precorrin-6A reductase. EC 1.3.1.106.. Co-precorrin-6B + NAD(+) = Co-precorrin-6A + NADH + H(+).

cobalt-precorrin-6B (C(15))-methyltransferase [decarboxylating] (EC 2.1.1.196)

cobalt-precorrin-6B (C(15))-methyltransferase [decarboxylating]. EC 2.1.1.196.. Co-precorrin-6B + S-adenosyl-L-methionine = Co-precorrin-7 + S-adenosyl-

cobalt-precorrin-7 (C(5))-methyltransferase (EC 2.1.1.289)

cobalt-precorrin-7 (C(5))-methyltransferase. EC 2.1.1.289.. Co-precorrin-7 + S-adenosyl-L-methionine = Co-precorrin-8X + S-adenosyl-

cobalt-precorrin-8 methylmutase (EC 5.4.99.60)

cobalt-precorrin-8 methylmutase. EC 5.4.99.60.. Co-precorrin-8X = cob(II)yrinate.