Enzymes A-Z
Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.
Enzymes A-Z
Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.
cardiolipin synthase (CMP-forming) (EC 2.7.8.41)
cardiolipin synthase (CMP-forming). EC 2.7.8.41.. a CDP-1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phospho-
caricain (EC 3.4.22.30)
caricain. EC 3.4.22.30.. Hydrolysis of proteins with broad specificity for peptide bonds, similar
carlactone synthase (EC 1.13.11.69)
carlactone synthase. EC 1.13.11.69.. 9-cis-10'-apo-beta-carotenal + 2 O2 = (2E,4E,6E)-7-hydroxy-4-methylhepta-
carminomycin 4-O-methyltransferase (EC 2.1.1.292)
carminomycin 4-O-methyltransferase. EC 2.1.1.292.. carminomycin + S-adenosyl-L-methionine = daunorubicin + S-adenosyl-L-
carnitinamidase (EC 3.5.1.73)
carnitinamidase. EC 3.5.1.73.. (R)-carnitinamide + H2O = (R)-carnitine + NH4(+).
carnitine 3-dehydrogenase (EC 1.1.1.108)
carnitine 3-dehydrogenase. EC 1.1.1.108.. carnitine + NAD(+) = 3-dehydrocarnitine + NADH + H(+).
carnitine decarboxylase (EC 4.1.1.42)
carnitine decarboxylase. EC 4.1.1.42.. carnitine + H(+) = 2-methylcholine + CO2.
carnitine monooxygenase (EC 1.14.13.239)
carnitine monooxygenase. EC 1.14.13.239.. (R)-carnitine + NADH + O2 + H(+) = (3R)-3-hydroxy-4-oxobutanoate +
carnitine O-acetyltransferase (EC 2.3.1.7)
carnitine O-acetyltransferase. EC 2.3.1.7.. (R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.
carnitine O-octanoyltransferase (EC 2.3.1.137)
carnitine O-octanoyltransferase. EC 2.3.1.137.. octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.
carnitine O-palmitoyltransferase (EC 2.3.1.21)
carnitine O-palmitoyltransferase. EC 2.3.1.21.. (R)-carnitine + hexadecanoyl-CoA = O-hexadecanoyl-(R)-carnitine + CoA.
carnitine--CoA ligase (EC 6.2.1.48)
carnitine--CoA ligase. EC 6.2.1.48.. (R)-carnitine + ATP + CoA = (R)-carnitinyl-CoA + AMP + diphosphate.
carnosic acid synthase (EC 1.14.14.61)
carnosic acid synthase. EC 1.14.14.61.. 11-hydroxyferruginol + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 =
carnosine N-methyltransferase (EC 2.1.1.22)
carnosine N-methyltransferase. EC 2.1.1.22.. carnosine + S-adenosyl-L-methionine = anserine + S-adenosyl-L-
carnosine synthase (EC 6.3.2.11)
carnosine synthase. EC 6.3.2.11.. beta-alanine + L-histidine + ATP = carnosine + ADP + phosphate + H(+).
carotene epsilon-hydroxylase (EC 1.14.14.158)
carotene epsilon-hydroxylase. EC 1.14.14.158.. (1) alpha-carotene + reduced [NADPH--hemoprotein reductase] + O2 = alpha-
carotenoid 1,2-hydratase (EC 4.2.1.131)
carotenoid 1,2-hydratase. EC 4.2.1.131.. (1) rhodopin = all-trans-lycopene + H2O.
carotenoid 9,10-dioxygenase (EC 1.14.99.n4)
carotenoid 9,10-dioxygenase. EC 1.14.99.n4.. all-trans-zeaxanthin + 2 O2 = 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial
carotenoid chi-ring synthase (EC 1.3.99.40)
carotenoid chi-ring synthase. EC 1.3.99.40.. a carotenoid beta-end derivative + 2 A = a carotenoid chi-end derivative
carotenoid isomerooxygenase (EC 1.13.11.65)
carotenoid isomerooxygenase. EC 1.13.11.65.. all-trans-zeaxanthin + O2 = (3R)-11-cis-3-hydroxyretinal + (3R)-all-
carotenoid phi-ring synthase (EC 1.3.99.39)
carotenoid phi-ring synthase. EC 1.3.99.39.. a carotenoid beta-end derivative + 2 A = a carotenoid phi-end derivative
carotenoid-9',10'-cleaving dioxygenase (EC 1.13.11.71)
carotenoid-9',10'-cleaving dioxygenase. EC 1.13.11.71.. all-trans-beta-carotene + O2 = beta-ionone + all-trans-10'-apo-beta-
carveol dehydrogenase (EC 1.1.1.243)
carveol dehydrogenase. EC 1.1.1.243.. (1S,5R)-carveol + NADP(+) = (R)-carvone + NADPH + H(+).
carvone reductase (EC 1.3.99.25)
carvone reductase. EC 1.3.99.25.. (1) (1R,4R)-dihydrocarvone + A = (R)-carvone + AH2.
casbene synthase (EC 4.2.3.8)
casbene synthase. EC 4.2.3.8.. (2E,6E,10E)-geranylgeranyl diphosphate = casbene + diphosphate.
caspase-1 (EC 3.4.22.36)
caspase-1. EC 3.4.22.36.. Strict requirement for an Asp residue at position P1 and has a preferred
caspase-10 (EC 3.4.22.63)
caspase-10. EC 3.4.22.63.. Strict requirement for Asp at position P1 and has a preferred cleavage
caspase-11 (EC 3.4.22.64)
caspase-11. EC 3.4.22.64.. Strict requirement for Asp at the P1 position and has a preferred
caspase-2 (EC 3.4.22.55)
caspase-2. EC 3.4.22.55.. Strict requirement for an Asp residue at P1, with 316-Asp being essential
caspase-3 (EC 3.4.22.56)
caspase-3. EC 3.4.22.56.. Strict requirement for an Asp residue at positions P1 and P4. It has a
caspase-4 (EC 3.4.22.57)
caspase-4. EC 3.4.22.57.. Strict requirement for Asp at the P1 position. It has a preferred
caspase-5 (EC 3.4.22.58)
caspase-5. EC 3.4.22.58.. Strict requirement for Asp at the P1 position. It has a preferred
caspase-6 (EC 3.4.22.59)
caspase-6. EC 3.4.22.59.. Strict requirement for Asp at position P1 and has a preferred cleavage
caspase-7 (EC 3.4.22.60)
caspase-7. EC 3.4.22.60.. Strict requirement for an Asp residue at position P1 and has a preferred
caspase-8 (EC 3.4.22.61)
caspase-8. EC 3.4.22.61.. Strict requirement for Asp at position P1 and has a preferred cleavage
caspase-9 (EC 3.4.22.62)
caspase-9. EC 3.4.22.62.. Strict requirement for an Asp residue at position P1 and with a marked
catalase (EC 1.11.1.6)
catalase. EC 1.11.1.6.. 2 H2O2 = O2 + 2 H2O.
catalase peroxidase (EC 1.11.1.21)
catalase peroxidase. EC 1.11.1.21.. (1) H2O2 + AH2 = A + 2 H2O.
catechol 1,2-dioxygenase (EC 1.13.11.1)
catechol 1,2-dioxygenase. EC 1.13.11.1.. catechol + O2 = cis,cis-muconate + 2 H(+).
catechol 2,3-dioxygenase (EC 1.13.11.2)
catechol 2,3-dioxygenase. EC 1.13.11.2.. catechol + O2 = (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H(+).
catechol O-methyltransferase (EC 2.1.1.6)
catechol O-methyltransferase. EC 2.1.1.6.. a catechol + S-adenosyl-L-methionine = a guaiacol + S-adenosyl-L-
catechol oxidase (dimerizing) (EC 1.1.3.14)
catechol oxidase (dimerizing). EC 1.1.3.14.. 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O.
catechol oxidase (EC 1.10.3.1)
catechol oxidase. EC 1.10.3.1.. 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O.
catharanthine synthase (EC 5.5.1.37)
catharanthine synthase. EC 5.5.1.37.. dehydrosecodine = catharanthine.
cathepsin B (EC 3.4.22.1)
cathepsin B. EC 3.4.22.1.. Hydrolysis of proteins with broad specificity for peptide bonds.
cathepsin D (EC 3.4.23.5)
cathepsin D. EC 3.4.23.5.. Specificity similar to, but narrower than, that of pepsin A. Does not
cathepsin E (EC 3.4.23.34)
cathepsin E. EC 3.4.23.34.. Similar to cathepsin D, but slightly broader specificity.
cathepsin F (EC 3.4.22.41)
cathepsin F. EC 3.4.22.41.. The recombinant enzyme cleaves synthetic substrates with Phe and Leu
cathepsin G (EC 3.4.21.20)
cathepsin G. EC 3.4.21.20.. Specificity similar to chymotrypsin C.
cathepsin H (EC 3.4.22.16)
cathepsin H. EC 3.4.22.16.. Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving
cathepsin K (EC 3.4.22.38)
cathepsin K. EC 3.4.22.38.. Broad proteolytic activity. With small-molecule substrates and
cathepsin L (EC 3.4.22.15)
cathepsin L. EC 3.4.22.15.. Specificity close to that of papain. As compared to cathepsin B,
cathepsin O (EC 3.4.22.42)
cathepsin O. EC 3.4.22.42.. The recombinant human enzyme hydrolyzes synthetic endopeptidase
cathepsin S (EC 3.4.22.27)
cathepsin S. EC 3.4.22.27.. Similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec,
cathepsin T (EC 3.4.22.24)
cathepsin T. EC 3.4.22.24.. Interconversion of the three forms of EC 2.6.1.5.
cathepsin V (EC 3.4.22.43)
cathepsin V. EC 3.4.22.43.. The recombinant enzyme hydrolyzes proteins (serum albumin, collagen) and
cathepsin X (EC 3.4.18.1)
cathepsin X. EC 3.4.18.1.. Release of C-terminal amino acid residues with broad specificity,
cattleyene synthase (EC 4.2.3.225)
cattleyene synthase. EC 4.2.3.225.. (2E,6E,10E)-geranylgeranyl diphosphate = cattleyene + diphosphate.
CC-preferring endodeoxyribonuclease (EC 3.1.21.6)
CC-preferring endodeoxyribonuclease. EC 3.1.21.6.. endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products,
CCA tRNA nucleotidyltransferase (EC 2.7.7.72)
CCA tRNA nucleotidyltransferase. EC 2.7.7.72.. a tRNA precursor + 2 CTP + ATP = a tRNA with a 3' CCA end +