Enzymes A-Z
Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.
Enzymes A-Z
Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.
calcidiol 1-monooxygenase (EC 1.14.15.18)
calcidiol 1-monooxygenase. EC 1.14.15.18.. (1) calcidiol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = calcitriol +
calcium-regulated photoprotein (EC 1.13.12.24)
calcium-regulated photoprotein. EC 1.13.12.24.. apo-[aequorin] + coelenterazine + 3 Ca(2+) + O2 = excited state-
calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)
calcium/calmodulin-dependent protein kinase. EC 2.7.11.17.. (1) L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).
caldariellaquinol oxidase (H(+)-transporting) (EC 7.1.1.4)
caldariellaquinol oxidase (H(+)-transporting). EC 7.1.1.4.. 2 caldariellaquinol + O2 + n H(+)(in) = 2 caldariellaquinone + 2 H2O +
caldesmon-phosphatase (EC 3.1.3.55)
caldesmon-phosphatase. EC 3.1.3.55.. [caldesmon] phosphate + H2O = [caldesmon] + phosphate.
caldopentamine synthase (EC 2.5.1.127)
caldopentamine synthase. EC 2.5.1.127.. norspermine + S-adenosyl 3-(methylsulfanyl)propylamine = caldopentamine +
calicivirin (EC 3.4.22.66)
calicivirin. EC 3.4.22.66.. Endopeptidase with a preference for cleavage when the P1 position is
calmodulin-lysine N-methyltransferase (EC 2.1.1.60)
calmodulin-lysine N-methyltransferase. EC 2.1.1.60.. [calmodulin]-L-lysine + S-adenosyl-L-methionine = [calmodulin]-N(6)-
calpain-1 (EC 3.4.22.52)
calpain-1. EC 3.4.22.52.. Broad endopeptidase specificity.
calpain-2 (EC 3.4.22.53)
calpain-2. EC 3.4.22.53.. Broad endopeptidase specificity.
calpain-3 (EC 3.4.22.54)
calpain-3. EC 3.4.22.54.. Broad endopeptidase activity.
camalexin synthase (EC 1.14.19.52)
camalexin synthase. EC 1.14.19.52.. 2-(L-cystein-S-yl)-2-(1H-indol-3-yl)-acetonitrile + 2 reduced [NADPH-
camelliol C synthase (EC 5.4.99.38)
camelliol C synthase. EC 5.4.99.38.. (S)-2,3-epoxysqualene = camelliol C.
cAMP deaminase (EC 3.5.4.46)
cAMP deaminase. EC 3.5.4.46.. 3',5'-cyclic AMP + H2O + H(+) = 3',5'-cyclic IMP + NH4(+).
cAMP-dependent protein kinase (EC 2.7.11.11)
cAMP-dependent protein kinase. EC 2.7.11.11.. (1) L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).
camphor 5-monooxygenase (EC 1.14.15.1)
camphor 5-monooxygenase. EC 1.14.15.1.. 2 reduced [2Fe-2S]-[putidaredoxin] + (1R,4R)-camphor + O2 + 2 H(+) =
canavanine-gamma-lyase (EC 4.4.1.43)
canavanine-gamma-lyase. EC 4.4.1.43.. L-canavanine + H2O = N-hydroxyguanidine + L-homoserine.
cancer procoagulant (EC 3.4.22.26)
cancer procoagulant. EC 3.4.22.26.. Specific cleavage of Arg-|-Ile bond in Factor X to form Factor Xa.
candidapepsin (EC 3.4.23.24)
candidapepsin. EC 3.4.23.24.. Preferential cleavage at the carboxyl of hydrophobic amino acids,
cannabidiolic acid synthase (EC 1.21.3.8)
cannabidiolic acid synthase. EC 1.21.3.8.. cannabigerolate + O2 = cannabidiolate + H2O2.
capreomycidine synthase (EC 4.2.1.145)
capreomycidine synthase. EC 4.2.1.145.. (2S,3S)-hydroxyarginine = (2S,3R)-capreomycidine + H2O.
capsaicin synthase (EC 2.3.2.35)
capsaicin synthase. EC 2.3.2.35.. vanillylamine + (6E)-8-methylnon-6-enoyl-CoA = capsaicin + CoA + H(+).
capsanthin/capsorubin synthase (EC 5.3.99.8)
capsanthin/capsorubin synthase. EC 5.3.99.8.. (1) all-trans-violaxanthin = all-trans-capsorubin.
capsular-polysaccharide endo-1,3-alpha-galactosidase (EC 3.2.1.87)
capsular-polysaccharide endo-1,3-alpha-galactosidase. EC 3.2.1.87.. Random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter
carbamate kinase (EC 2.7.2.2)
carbamate kinase. EC 2.7.2.2.. hydrogencarbonate + NH4(+) + ATP = carbamoyl phosphate + ADP + H2O +
carbamoyl-phosphate synthase (ammonia) (EC 6.3.4.16)
carbamoyl-phosphate synthase (ammonia). EC 6.3.4.16.. hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP +
carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5)
carbamoyl-phosphate synthase (glutamine-hydrolyzing). EC 6.3.5.5.. hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate +
carbamoyl-serine ammonia-lyase (EC 4.3.1.13)
carbamoyl-serine ammonia-lyase. EC 4.3.1.13.. O-carbamoyl-L-serine + H2O + H(+) = pyruvate + 2 NH4(+) + CO2.
carbapenam-3-carboxylate synthase (EC 6.3.3.6)
carbapenam-3-carboxylate synthase. EC 6.3.3.6.. (2S,5S)-5-carboxymethylproline + ATP = (3S,5S)-carbapenam-3-caboxylate +
carbazole 1,9a-dioxygenase (EC 1.14.12.22)
carbazole 1,9a-dioxygenase. EC 1.14.12.22.. (1) 9H-carbazole + NADH + O2 + H(+) = 2'-aminobiphenyl-2,3-diol + NAD(+).
carbendazim hydrolysing esterase (EC 3.1.1.122)
carbendazim hydrolysing esterase. EC 3.1.1.122.. carbendazim + H2O = 2-aminobenzimidazole + methanol + CO2.
carbon disulfide hydrolase (EC 3.13.1.5)
carbon disulfide hydrolase. EC 3.13.1.5.. carbon disulfide + 2 H2O = 2 hydrogen sulfide + CO2 + 2 H(+).
carbonic anhydrase (EC 4.2.1.1)
carbonic anhydrase. EC 4.2.1.1.. hydrogencarbonate + H(+) = CO2 + H2O.
carbonyl reductase (NADPH) (EC 1.1.1.184)
carbonyl reductase (NADPH). EC 1.1.1.184.. a secondary alcohol + NADP(+) = a ketone + NADPH + H(+).
carbonyl sulfide hydrolase (EC 3.13.1.7)
carbonyl sulfide hydrolase. EC 3.13.1.7.. carbonyl sulfide + H2O = hydrogen sulfide + CO2 + H(+).
carboxy-cis,cis-muconate cyclase (EC 5.5.1.5)
carboxy-cis,cis-muconate cyclase. EC 5.5.1.5.. 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate.
carboxyaminopropylagmatine decarboxylase (EC 4.1.1.127)
carboxyaminopropylagmatine decarboxylase. EC 4.1.1.127.. N(1)-[(S)-3-amino-3-carboxypropyl]agmatine + H(+) = N(1)-
carboxyaminopropylagmatine dehydrogenase (EC 1.5.1.55)
carboxyaminopropylagmatine dehydrogenase. EC 1.5.1.55.. N(1)-[(S)-3-amino-3-carboxypropyl]agmatine + NADP(+) + H2O = L-aspartate
carboxybiotin decarboxylase (EC 7.2.4.1)
carboxybiotin decarboxylase. EC 7.2.4.1.. N(6)-carboxybiotinyl-L-lysyl-[protein] + n Na(+)(in) + H(+) = N(6)-
carboxylate reductase (EC 1.2.99.6)
carboxylate reductase. EC 1.2.99.6.. an aldehyde + A + H2O = a carboxylate + AH2 + H(+).
carboxylate reductase (NADP(+)) (EC 1.2.1.30)
carboxylate reductase (NADP(+)). EC 1.2.1.30.. an aromatic aldehyde + AMP + diphosphate + NADP(+) =
carboxylesterase (EC 3.1.1.1)
carboxylesterase. EC 3.1.1.1.. a carboxylic ester + H2O = an alcohol + a carboxylate + H(+).
carboxymethylcellulase (EC 3.2.1.203)
carboxymethylcellulase. EC 3.2.1.203.. Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
carboxymethylenebutenolidase (EC 3.1.1.45)
carboxymethylenebutenolidase. EC 3.1.1.45.. 2-(5-oxo-2,5-dihydrofuran-2-ylidene)acetate + H2O = 4-oxohex-2-enedioate
carboxymethylhydantoinase (EC 3.5.2.4)
carboxymethylhydantoinase. EC 3.5.2.4.. L-5-carboxymethylhydantoin + H2O = N-carbamoyl-L-aspartate + H(+).
carboxymethyloxysuccinate lyase (EC 4.2.99.12)
carboxymethyloxysuccinate lyase. EC 4.2.99.12.. carboxymethoxysuccinate = glycolate + fumarate.
carboxymethylproline synthase (EC 2.3.1.226)
carboxymethylproline synthase. EC 2.3.1.226.. (S)-1-pyrroline-5-carboxylate + malonyl-CoA + H2O + H(+) = (2S,5S)-5-
carboxynorspermidine decarboxylase (EC 4.1.1.96)
carboxynorspermidine decarboxylase. EC 4.1.1.96.. (1) carboxynorspermidine + H(+) = norspermidine + CO2.
carboxynorspermidine synthase (EC 1.5.1.43)
carboxynorspermidine synthase. EC 1.5.1.43.. (1) carboxynorspermidine + NADP(+) + H2O = L-aspartate 4-semialdehyde +
carboxypeptidase A (EC 3.4.17.1)
carboxypeptidase A. EC 3.4.17.1.. Release of a C-terminal amino acid, but little or no action with -Asp,
carboxypeptidase A2 (EC 3.4.17.15)
carboxypeptidase A2. EC 3.4.17.15.. Similar to that of carboxypeptidase A (EC 3.4.17.1), but with a
carboxypeptidase B (EC 3.4.17.2)
carboxypeptidase B. EC 3.4.17.2.. Preferential release of a C-terminal lysine or arginine amino acid.
carboxypeptidase C (EC 3.4.16.5)
carboxypeptidase C. EC 3.4.16.5.. Release of a C-terminal amino acid with broad specificity.
carboxypeptidase D (EC 3.4.16.6)
carboxypeptidase D. EC 3.4.16.6.. Preferential release of a C-terminal arginine or lysine residue.
carboxypeptidase E (EC 3.4.17.10)
carboxypeptidase E. EC 3.4.17.10.. Release of C-terminal arginine or lysine residues from polypeptides.
carboxypeptidase M (EC 3.4.17.12)
carboxypeptidase M. EC 3.4.17.12.. Cleavage of C-terminal arginine or lysine residues from polypeptides.
carboxypeptidase T (EC 3.4.17.18)
carboxypeptidase T. EC 3.4.17.18.. Releases a C-terminal residue, which may be hydrophobic or positively
carboxypeptidase Taq (EC 3.4.17.19)
carboxypeptidase Taq. EC 3.4.17.19.. Release of a C-terminal amino acid with broad specificity, except for
carboxypeptidase U (EC 3.4.17.20)
carboxypeptidase U. EC 3.4.17.20.. Release of C-terminal Arg and Lys from a polypeptide.
carboxyvinyl-carboxyphosphonate phosphorylmutase (EC 2.7.8.23)
carboxyvinyl-carboxyphosphonate phosphorylmutase. EC 2.7.8.23.. 1-carboxyvinyl carboxyphosphonate + H(+) =