Enzymes A-Z
Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.
Enzymes A-Z
Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.
biphenyl 2,3-dioxygenase (EC 1.14.12.18)
biphenyl 2,3-dioxygenase. EC 1.14.12.18.. biphenyl + NADH + O2 + H(+) = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-
biphenyl-2,3-diol 1,2-dioxygenase (EC 1.13.11.39)
biphenyl-2,3-diol 1,2-dioxygenase. EC 1.13.11.39.. biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate +
bis-gamma-glutamylcystine reductase (EC 1.8.1.13)
bis-gamma-glutamylcystine reductase. EC 1.8.1.13.. 2 gamma-L-glutamyl-L-cysteine + NADP(+) = bis-gamma-glutamylcystine +
bis(2-ethylhexyl)phthalate esterase (EC 3.1.1.60)
bis(2-ethylhexyl)phthalate esterase. EC 3.1.1.60.. bis(2-ethylhexyl)phthalate + H2O = 2-ethylhexan-1-ol + 2-ethylhexyl
bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29)
bis(5'-adenosyl)-triphosphatase. EC 3.6.1.29.. P(1),P(3)-bis(5'-adenosyl) triphosphate + H2O = AMP + ADP + 2 H(+).
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17)
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical). EC 3.6.1.17.. P(1),P(4)-bis(5'-guanosyl) tetraphosphate + H2O = GMP + GTP + 2 H(+).
bis(5'-nucleosyl)-tetraphosphatase (symmetrical) (EC 3.6.1.41)
bis(5'-nucleosyl)-tetraphosphatase (symmetrical). EC 3.6.1.41.. P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP + 2 H(+).
bisanhydrobacterioruberin hydratase (EC 4.2.1.161)
bisanhydrobacterioruberin hydratase. EC 4.2.1.161.. bacterioruberin = bisanhydrobacterioruberin + 2 H2O.
bisdemethoxycurcumin synthase (EC 2.3.1.211)
bisdemethoxycurcumin synthase. EC 2.3.1.211.. 2 4-coumaroyl-CoA + malonyl-CoA + H2O + H(+) = bisdemethoxycurcumin +
bisphosphoglycerate mutase (EC 5.4.2.4)
bisphosphoglycerate mutase. EC 5.4.2.4.. (2R)-3-phospho-glyceroyl phosphate = (2R)-2,3-bisphosphoglycerate + H(+).
bisphosphomevalonate decarboxylase (EC 4.1.1.110)
bisphosphomevalonate decarboxylase. EC 4.1.1.110.. (R)-3,5-bisphosphomevalonate + H(+) = isopentenyl phosphate + CO2 +
bisucaberin synthase (EC 6.3.2.64)
bisucaberin synthase. EC 6.3.2.64.. 2 N-(3-carboxypropanoyl)-N-hydroxycadaverine + 2 ATP = bisucaberin +
biuret amidohydrolase (EC 3.5.1.84)
biuret amidohydrolase. EC 3.5.1.84.. biuret + H2O = urea-1-carboxylate + NH4(+).
blasticidin-S deaminase (EC 3.5.4.23)
blasticidin-S deaminase. EC 3.5.4.23.. blasticidin S + H2O + H(+) = deaminohydroxyblasticidin S + NH4(+).
bleomycin hydrolase (EC 3.4.22.40)
bleomycin hydrolase. EC 3.4.22.40.. Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis
blood group B branched chain alpha-1,3-galactosidase (EC 3.2.1.n1)
blood group B branched chain alpha-1,3-galactosidase. EC 3.2.1.n1.. Hydrolysis of terminal, non-reducing branched (1->3)-alpha-D-galactosidic
blood group B linear chain alpha-1,3-galactosidase (EC 3.2.1.n2)
blood group B linear chain alpha-1,3-galactosidase. EC 3.2.1.n2.. Hydrolysis of terminal, non-reducing linear (1->3)-alpha-D-galactosidic
blood-group-substance endo-1,4-beta-galactosidase (EC 3.2.1.102)
blood-group-substance endo-1,4-beta-galactosidase. EC 3.2.1.102.. Endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A
bonnadiene synthase (EC 4.2.3.223)
bonnadiene synthase. EC 4.2.3.223.. (2E,6E,10E)-geranylgeranyl diphosphate = bonnadiene + diphosphate.
bontoxilysin (EC 3.4.24.69)
bontoxilysin. EC 3.4.24.69.. Limited hydrolysis of proteins of the neuroexocytosis apparatus,
bothrolysin (EC 3.4.24.50)
bothrolysin. EC 3.4.24.50.. Cleavage of 4-Gln-|-His-5, 9-Ser-|-His-10 and 14-Ala-|-Leu-15 of insulin
bothropasin (EC 3.4.24.49)
bothropasin. EC 3.4.24.49.. Cleavage of 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-15,
botryococcene C-methyltransferase (EC 2.1.1.263)
botryococcene C-methyltransferase. EC 2.1.1.263.. C30 botryococcene + 2 S-adenosyl-L-methionine = 3,20-dimethyl-1,2,21,22-
botryococcene synthase (EC 1.3.1.97)
botryococcene synthase. EC 1.3.1.97.. C30 botryococcene + diphosphate + NADP(+) = presqualene diphosphate +
Botryococcus squalene synthase (EC 1.3.1.96)
Botryococcus squalene synthase. EC 1.3.1.96.. presqualene diphosphate + NADPH + H(+) = squalene + diphosphate +
brachyurin (EC 3.4.21.32)
brachyurin. EC 3.4.21.32.. Hydrolysis of proteins, with broad specificity for peptide bonds. Native
branched primary-alkylsulfatase (EC 3.1.6.22)
branched primary-alkylsulfatase. EC 3.1.6.22.. 2-butyloctyl sulfate + H2O = 2-butyloctan-1-ol + sulfate + H(+).
branched-chain 2-oxoacid:malonyl-[acyl-carrier protein] acyltransferase (EC 2.3.1.328)
branched-chain 2-oxoacid:malonyl-[acyl-carrier protein] acyltransferase. EC 2.3.1.328.. N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + 4-methyl-2-
branched-chain alpha-keto acid dehydrogenase system (EC 1.2.1.25)
branched-chain alpha-keto acid dehydrogenase system. EC 1.2.1.25.. 3-methyl-2-oxobutanoate + NAD(+) + CoA = 2-methylpropanoyl-CoA + CO2 +
branched-chain beta-ketoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.300)
branched-chain beta-ketoacyl-[acyl-carrier-protein] synthase. EC 2.3.1.300.. (1) 3-methylbutanoyl-CoA + malonyl-[ACP] + H(+) = 5-methyl-3-oxohexanoyl-
branched-chain-2-oxoacid decarboxylase (EC 4.1.1.72)
branched-chain-2-oxoacid decarboxylase. EC 4.1.1.72.. (S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO2.
branched-chain-amino-acid transaminase (EC 2.6.1.42)
branched-chain-amino-acid transaminase. EC 2.6.1.42.. L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
branched-chain-fatty-acid kinase (EC 2.7.2.14)
branched-chain-fatty-acid kinase. EC 2.7.2.14.. 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP.
branched-dextran exo-1,2-alpha-glucosidase (EC 3.2.1.115)
branched-dextran exo-1,2-alpha-glucosidase. EC 3.2.1.115.. Hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of
brassinolide synthase (EC 1.14.14.180)
brassinolide synthase. EC 1.14.14.180.. castasterone + reduced [NADPH--hemoprotein reductase] + O2 = brassinolide
brassinosteroid 6-oxygenase (EC 1.14.14.179)
brassinosteroid 6-oxygenase. EC 1.14.14.179.. 6-deoxocastasterone + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 =
brevianamide F prenyltransferase (deoxybrevianamide E-forming) (EC 2.5.1.109)
brevianamide F prenyltransferase (deoxybrevianamide E-forming). EC 2.5.1.109.. brevianamide F + dimethylallyl diphosphate = deoxybrevianamide E +
bromide peroxidase (EC 1.11.1.18)
bromide peroxidase. EC 1.11.1.18.. RH + Br(-) + H2O2 = RBr + 2 H2O.
bromoxynil nitrilase (EC 3.5.5.6)
bromoxynil nitrilase. EC 3.5.5.6.. 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxybenzoate
bursehernin 5'-monooxygenase (EC 1.14.14.131)
bursehernin 5'-monooxygenase. EC 1.14.14.131.. (-)-bursehernin + reduced [NADPH--hemoprotein reductase] + O2 = (-)-
butanal dehydrogenase (EC 1.2.1.57)
butanal dehydrogenase. EC 1.2.1.57.. (1) butanal + NAD(+) + CoA = butanoyl-CoA + NADH + H(+).
butane monooxygenase (soluble) (EC 1.14.13.230)
butane monooxygenase (soluble). EC 1.14.13.230.. butane + NADH + O2 + H(+) = butan-1-ol + NAD(+) + H2O.
butanoyl-CoA dehydrogenase complex (NAD(+), ferredoxin) (EC 1.3.1.109)
butanoyl-CoA dehydrogenase complex (NAD(+), ferredoxin). EC 1.3.1.109.. butanoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 NAD(+) = (2E)-
butyrate kinase (EC 2.7.2.7)
butyrate kinase. EC 2.7.2.7.. butanoate + ATP = butanoyl phosphate + ADP.
butyrate--acetoacetate CoA-transferase (EC 2.8.3.9)
butyrate--acetoacetate CoA-transferase. EC 2.8.3.9.. acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate.
C-19 steroid 1alpha-hydroxylase (EC 1.14.15.19)
C-19 steroid 1alpha-hydroxylase. EC 1.14.15.19.. testosterone + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 1alpha-
C-glycoside oxidase (EC 1.1.3.50)
C-glycoside oxidase. EC 1.1.3.50.. carminate + O2 = 3'-dehydrocarminate + H2O2.
C-phycocyanin alpha-cysteine-84 phycocyanobilin lyase (EC 4.4.1.32)
C-phycocyanin alpha-cysteine-84 phycocyanobilin lyase. EC 4.4.1.32.. phycocyanobilin-L-cysteinyl(84)-[C-phycocyanin alpha-subunit] = apo-L-
C-phycoerythrin alpha-cysteine-82 phycoerythrobilin lyase (EC 4.4.1.39)
C-phycoerythrin alpha-cysteine-82 phycoerythrobilin lyase. EC 4.4.1.39.. phycoerythrobilin-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit] = apo-
C-phycoerythrin beta-cysteine-48/59 phycoerythrobilin lyase (EC 4.4.1.40)
C-phycoerythrin beta-cysteine-48/59 phycoerythrobilin lyase. EC 4.4.1.40.. phycoerythrobilin-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-
C-terminal processing peptidase (EC 3.4.21.102)
C-terminal processing peptidase. EC 3.4.21.102.. The enzyme shows specific recognition of a C-terminal tripeptide, Xaa-
C5a peptidase (EC 3.4.21.110)
C5a peptidase. EC 3.4.21.110.. The primary cleavage site is at 67-His-|-Lys-68 in human C5a with a minor
C7-cyclitol 7-kinase (EC 2.7.1.214)
C7-cyclitol 7-kinase. EC 2.7.1.214.. (1) valienone + ATP = valienone 7-phosphate + ADP + H(+).
caffeate 3,4-dioxygenase (EC 1.13.11.22)
caffeate 3,4-dioxygenase. EC 1.13.11.22.. (E)-caffeate + O2 = 3-(2-carboxyethenyl)-cis,cis-muconate + 2 H(+).
caffeate CoA-transferase (EC 2.8.3.23)
caffeate CoA-transferase. EC 2.8.3.23.. hydrocaffeoyl-CoA + (E)-caffeate = 3-(3,4-dihydroxyphenyl)propanoate +
caffeate O-methyltransferase (EC 2.1.1.68)
caffeate O-methyltransferase. EC 2.1.1.68.. (E)-caffeate + S-adenosyl-L-methionine = (E)-ferulate + S-adenosyl-L-
caffeine dehydrogenase (EC 1.17.5.2)
caffeine dehydrogenase. EC 1.17.5.2.. caffeine + a ubiquinone + H2O = 1,3,7-trimethylurate + a ubiquinol.
caffeine synthase (EC 2.1.1.160)
caffeine synthase. EC 2.1.1.160.. (1) theobromine + S-adenosyl-L-methionine = caffeine + S-adenosyl-L-
caffeoyl-CoA O-methyltransferase (EC 2.1.1.104)
caffeoyl-CoA O-methyltransferase. EC 2.1.1.104.. (E)-caffeoyl-CoA + S-adenosyl-L-methionine = (E)-feruloyl-CoA +
caffeoyl-CoA reductase (EC 1.3.1.108)
caffeoyl-CoA reductase. EC 1.3.1.108.. hydrocaffeoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 NAD(+) = (E)-