Biochemistry & Enzymes

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Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase (EC 1.3.1.53)

(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase. EC 1.3.1.53.. (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) =

(3S,6E)-nerolidol synthase (EC 4.2.3.48)

(3S,6E)-nerolidol synthase. EC 4.2.3.48.. (2E,6E)-farnesyl diphosphate + H2O = (3S,6E)-nerolidol + diphosphate.

(3S)-(+)-asterisca-2(9),6-diene synthase (EC 4.2.3.161)

(3S)-(+)-asterisca-2(9),6-diene synthase. EC 4.2.3.161.. (2E,6E)-farnesyl diphosphate = (3S)-(+)-asterisca-2(9),6-diene +

(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier (EC 1.14.14.15)

(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier. EC 1.14.14.15.. (3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[SgcC2 peptidyl-

(3S)-3-hydroxy-D-aspartate dehydratase (EC 4.2.1.184)

(3S)-3-hydroxy-D-aspartate dehydratase. EC 4.2.1.184.. (3S)-3-hydroxy-D-aspartate = iminosuccinate + H2O.

(3S)-malyl-CoA thioesterase (EC 3.1.2.30)

(3S)-malyl-CoA thioesterase. EC 3.1.2.30.. (S)-malyl-CoA + H2O = (S)-malate + CoA + H(+).

(4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2- (EC 2.5.1.131)

(4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-. EC 2.5.1.131.. gamma-L-glutamyltyramine + [5-(aminomethyl)furan-3-yl]methyl diphosphate

(4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase (EC 1.3.1.113)

(4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase. EC 1.3.1.113.. a [(3S,4R)-4-alkanoyl-5-oxooxolan-3-yl]methyl phosphate + NADP(+) =

(4-hydroxyphenyl)alkanoate synthase (EC 2.3.1.261)

(4-hydroxyphenyl)alkanoate synthase. EC 2.3.1.261.. (1) 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 8 malonyl-CoA +

(4-O-methyl)-D-glucuronate--lignin esterase (EC 3.1.1.117)

(4-O-methyl)-D-glucuronate--lignin esterase. EC 3.1.1.117.. a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-O-methyl-

(4S)-4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.42)

(4S)-4-hydroxy-2-oxoglutarate aldolase. EC 4.1.3.42.. (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate.

(4S)-4-hydroxy-5-phosphooxypentane-2,3-dione isomerase (EC 5.3.1.32)

(4S)-4-hydroxy-5-phosphooxypentane-2,3-dione isomerase. EC 5.3.1.32.. (2S)-2-hydroxy-3,4-dioxopentyl phosphate = 3-hydroxy-2,4-dioxopentyl

(4S)-beta-phellandrene synthase (geranyl-diphosphate-cyclizing) (EC 4.2.3.52)

(4S)-beta-phellandrene synthase (geranyl-diphosphate-cyclizing). EC 4.2.3.52.. (2E)-geranyl diphosphate = (-)-beta-phellandrene + diphosphate.

(4S)-limonene synthase (EC 4.2.3.16)

(4S)-limonene synthase. EC 4.2.3.16.. (2E)-geranyl diphosphate = (4S)-limonene + diphosphate.

(5-formylfuran-3-yl)methyl phosphate synthase (EC 4.2.3.153)

(5-formylfuran-3-yl)methyl phosphate synthase. EC 4.2.3.153.. 2 D-glyceraldehyde 3-phosphate = 4-(hydroxymethyl)-2-furancarboxaldehyde

(5-formylfuran-3-yl)methyl phosphate transaminase (EC 2.6.1.108)

(5-formylfuran-3-yl)methyl phosphate transaminase. EC 2.6.1.108.. 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + L-alanine =

(5R)-carbapenem-3-carboxylate synthase (EC 1.14.20.3)

(5R)-carbapenem-3-carboxylate synthase. EC 1.14.20.3.. (3S,5S)-carbapenam-3-caboxylate + 2-oxoglutarate + O2 = (5R)-carbapen-2-

(5S)-5-amino-3-oxohexanoate:acetyl-CoA ethylamine transferase (EC 2.3.1.247)

(5S)-5-amino-3-oxohexanoate:acetyl-CoA ethylamine transferase. EC 2.3.1.247.. (5S)-5-amino-3-oxohexanoate + acetyl-CoA = (3S)-3-aminobutanoyl-CoA +

(6-4)DNA photolyase (EC 4.1.99.13)

(6-4)DNA photolyase. EC 4.1.99.13.. (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA).

(aminoalkyl)phosphonate N-acetyltransferase (EC 2.3.1.280)

(aminoalkyl)phosphonate N-acetyltransferase. EC 2.3.1.280.. aminomethylphosphonate + acetyl-CoA = 2-N-acetamidomethylphosphonate +

(Ara-f)3-Hyp beta-L-arabinobiosidase (EC 3.2.1.187)

(Ara-f)3-Hyp beta-L-arabinobiosidase. EC 3.2.1.187.. 4-O-(beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl-(1->2)-beta-

(carboxyethyl)arginine beta-lactam-synthase (EC 6.3.3.4)

(carboxyethyl)arginine beta-lactam-synthase. EC 6.3.3.4.. N(2)-(2-carboxyethyl)-L-arginine + ATP = deoxyamidinoproclavaminate +

(d)CMP kinase (EC 2.7.4.25)

(d)CMP kinase. EC 2.7.4.25.. (1) CMP + ATP = CDP + ADP.

(d)CTP diphosphatase (EC 3.6.1.65)

(d)CTP diphosphatase. EC 3.6.1.65.. (1) CTP + H2O = CMP + diphosphate + H(+).

(deoxy)adenylate kinase (EC 2.7.4.11)

(deoxy)adenylate kinase. EC 2.7.4.11.. dAMP + ATP = dADP + ADP.

(deoxy)nucleoside-phosphate kinase (EC 2.7.4.13)

(deoxy)nucleoside-phosphate kinase. EC 2.7.4.13.. a 2'-deoxyribonucleoside 5'-phosphate + ATP = a 2'-deoxyribonucleoside

(E,E)-germacrene B synthase (EC 4.2.3.71)

(E,E)-germacrene B synthase. EC 4.2.3.71.. (2E,6E)-farnesyl diphosphate = (1E,4E)-germacrene B + diphosphate.

(E)-2-epi-beta-caryophyllene synthase (EC 4.2.3.137)

(E)-2-epi-beta-caryophyllene synthase. EC 4.2.3.137.. (2E,6E)-farnesyl diphosphate = (E)-2-epi-beta-caryophyllene +

(E)-2-methylbutanal oxime monooxygenase (EC 1.14.14.41)

(E)-2-methylbutanal oxime monooxygenase. EC 1.14.14.41.. (1) (1E,2S)-2-methylbutanal oxime + reduced [NADPH--hemoprotein

(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) (EC 1.17.7.1)

(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin). EC 1.17.7.1.. (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 oxidized [2Fe-2S]-

(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) (EC 1.17.7.3)

(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin). EC 1.17.7.3.. (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + oxidized [flavodoxin] +

(E)-benzylidenesuccinyl-CoA hydratase (EC 4.2.1.180)

(E)-benzylidenesuccinyl-CoA hydratase. EC 4.2.1.180.. (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA = (E)-2-benzylidenesuccinyl-

(E)-beta-ocimene synthase (EC 4.2.3.106)

(E)-beta-ocimene synthase. EC 4.2.3.106.. (2E)-geranyl diphosphate = (E)-beta-ocimene + diphosphate.

(E)-gamma-bisabolene synthase (EC 4.2.3.59)

(E)-gamma-bisabolene synthase. EC 4.2.3.59.. (2E,6E)-farnesyl diphosphate = (E)-gamma-bisabolene + diphosphate.

(E3-independent) E2 ubiquitin-conjugating enzyme (EC 2.3.2.24)

(E3-independent) E2 ubiquitin-conjugating enzyme. EC 2.3.2.24.. S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor

(hydroxyamino)benzene mutase (EC 5.4.4.1)

(hydroxyamino)benzene mutase. EC 5.4.4.1.. N-phenylhydroxylamine = 2-aminophenol.

(hydroxymethyl)phosphonate dioxygenase (EC 1.13.11.89)

(hydroxymethyl)phosphonate dioxygenase. EC 1.13.11.89.. hydroxymethylphosphonate + O2 = formate + phosphate + 2 H(+).

(indol-3-yl)acetyl-L-aspartate hydrolase (EC 3.5.1.134)

(indol-3-yl)acetyl-L-aspartate hydrolase. EC 3.5.1.134.. (indol-3-yl)acetyl-L-aspartate + H2O = (indol-3-yl)acetate + L-aspartate.

(iso)eugenol O-methyltransferase (EC 2.1.1.146)

(iso)eugenol O-methyltransferase. EC 2.1.1.146.. (E)-isoeugenol + S-adenosyl-L-methionine = (E)-isomethyleugenol +

(Kdo)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase (EC 2.4.99.13)

(Kdo)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase. EC 2.4.99.13.. an alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate =

(Kdo)2-lipid IVA (2-8) 3-deoxy-D-manno-octulosonic acid transferase (EC 2.4.99.14)

(Kdo)2-lipid IVA (2-8) 3-deoxy-D-manno-octulosonic acid transferase. EC 2.4.99.14.. alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-

(Kdo)3-lipid IVA (2-4) 3-deoxy-D-manno-octulosonic acid transferase (EC 2.4.99.15)

(Kdo)3-lipid IVA (2-4) 3-deoxy-D-manno-octulosonic acid transferase. EC 2.4.99.15.. alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) +

(methyl)glyoxal oxidase (EC 1.2.3.15)

(methyl)glyoxal oxidase. EC 1.2.3.15.. (1) glyoxal + O2 + H2O = glyoxylate + H2O2 + H(+).

(methylsulfanyl)alkanaldoxime N-monooxygenase (EC 1.14.14.43)

(methylsulfanyl)alkanaldoxime N-monooxygenase. EC 1.14.14.43.. an (E)-omega-(methylsulfanyl)-alkanal oxime + glutathione + reduced

(N-acetylneuraminyl)-galactosylglucosylceramide (EC 2.4.1.92)

(N-acetylneuraminyl)-galactosylglucosylceramide. EC 2.4.1.92.. a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine =

(phenol)carboxyphthiodiolenone synthase (EC 2.3.1.292)

(phenol)carboxyphthiodiolenone synthase. EC 2.3.1.292.. (1) icosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 2 (S)-

(R,R)-butanediol dehydrogenase (EC 1.1.1.4)

(R,R)-butanediol dehydrogenase. EC 1.1.1.4.. (R,R)-butane-2,3-diol + NAD(+) = (R)-acetoin + NADH + H(+).

(R,S)-reticuline 7-O-methyltransferase (EC 2.1.1.291)

(R,S)-reticuline 7-O-methyltransferase. EC 2.1.1.291.. (1) (S)-reticuline + S-adenosyl-L-methionine = (S)-laudanine +

(R)-1-hydroxy-2-aminoethylphosphonate ammonia-lyase (EC 4.3.1.33)

(R)-1-hydroxy-2-aminoethylphosphonate ammonia-lyase. EC 4.3.1.33.. (1R)-(2-amino-1-hydroxyethyl)phosphonate = phosphonoacetaldehyde +

(R)-2-haloacid dehalogenase (EC 3.8.1.9)

(R)-2-haloacid dehalogenase. EC 3.8.1.9.. an (R)-2-haloacid + H2O = a (2S)-2-hydroxycarboxylate + a halide anion +

(R)-2-hydroxy-4-methylpentanoate CoA-transferase (EC 2.8.3.24)

(R)-2-hydroxy-4-methylpentanoate CoA-transferase. EC 2.8.3.24.. 4-methylpentanoyl-CoA + (2R)-hydroxy-4-methylpentanoate = (R)-2-hydroxy-

(R)-2-hydroxy-fatty-acid dehydrogenase (EC 1.1.1.98)

(R)-2-hydroxy-fatty-acid dehydrogenase. EC 1.1.1.98.. (R)-2-hydroxyoctadecanoate + NAD(+) = 2-oxooctadecanoate + NADH + H(+).

(R)-2-hydroxyacyl-CoA dehydratase activating ATPase (EC 5.6.1.9)

(R)-2-hydroxyacyl-CoA dehydratase activating ATPase. EC 5.6.1.9.. 2 ATP + a reduced flavodoxin + an inactive (R)-2-hydroxyacyl-CoA

(R)-2-hydroxyglutarate--pyruvate transhydrogenase (EC 1.1.99.40)

(R)-2-hydroxyglutarate--pyruvate transhydrogenase. EC 1.1.99.40.. (R)-2-hydroxyglutarate + pyruvate = (R)-lactate + 2-oxoglutarate.

(R)-2-hydroxyglutaryl-CoA dehydratase (EC 4.2.1.167)

(R)-2-hydroxyglutaryl-CoA dehydratase. EC 4.2.1.167.. (R)-2-hydroxyglutaryl-CoA = (2E)-glutaconyl-CoA + H2O.

(R)-2-hydroxyisocaproyl-CoA dehydratase (EC 4.2.1.157)

(R)-2-hydroxyisocaproyl-CoA dehydratase. EC 4.2.1.157.. (R)-2-hydroxy-4-methylpentanoyl-CoA = 4-methylpent-2-enoyl-CoA + H2O.

(R)-2-methylmalate dehydratase (EC 4.2.1.35)

(R)-2-methylmalate dehydratase. EC 4.2.1.35.. (3R)-citramalate = 2-methylmaleate + H2O.

(R)-3-(aryl)lactoyl-CoA dehydratase (EC 4.2.1.175)

(R)-3-(aryl)lactoyl-CoA dehydratase. EC 4.2.1.175.. (1) (R)-3-phenyllactoyl-CoA = (E)-cinnamoyl-CoA + H2O.

(R)-3-[(carboxymethyl)amino]fatty acid dioxygenase/decarboxylase (EC 1.14.11.78)

(R)-3-[(carboxymethyl)amino]fatty acid dioxygenase/decarboxylase. EC 1.14.11.78.. a (3R)-3-[(carboxymethyl)amino]fatty acid + 2 2-oxoglutarate + 2 O2 =

(R)-3-amino-2-methylpropionate--pyruvate transaminase (EC 2.6.1.40)

(R)-3-amino-2-methylpropionate--pyruvate transaminase. EC 2.6.1.40.. (R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate +