Biochemistry & Enzymes

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Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

3beta-hydroxycholanate 3-dehydrogenase (NAD(+)) (EC 1.1.1.391)

3beta-hydroxycholanate 3-dehydrogenase (NAD(+)). EC 1.1.1.391.. 3-oxo-5beta-cholan-24-oate + NADH + H(+) = isolithocholate + NAD(+).

3beta-hydroxycholanate 3-dehydrogenase (NADP(+)) (EC 1.1.1.393)

3beta-hydroxycholanate 3-dehydrogenase (NADP(+)). EC 1.1.1.393.. 3-oxo-5beta-cholan-24-oate + NADPH + H(+) = isolithocholate + NADP(+).

3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270)

3beta-hydroxysteroid 3-dehydrogenase. EC 1.1.1.270.. a 3beta-hydroxysteroid + NADP(+) = a 3-oxosteroid + NADPH + H(+).

3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (EC 1.1.1.170)

3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase. EC 1.1.1.170.. (1) a 3beta-hydroxysteroid-4alpha-carboxylate + NADP(+) = a 3-oxosteroid

3beta-hydroxysteroid-4beta-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.417)

3beta-hydroxysteroid-4beta-carboxylate 3-dehydrogenase (decarboxylating). EC 1.1.1.417.. (1) a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + NAD(+) =

3beta,22alpha-dihydroxysteroid 3-dehydrogenase (EC 1.14.19.79)

3beta,22alpha-dihydroxysteroid 3-dehydrogenase. EC 1.14.19.79.. (1) (22S)-22-hydroxycampesterol + reduced [NADPH--hemoprotein reductase]

3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) (EC 3.7.1.22)

3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing). EC 3.7.1.22.. 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O = 5-deoxy-D-glucuronate +

4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase (EC 4.1.2.34)

4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase. EC 4.1.2.34.. (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H2O = 2-formylbenzoate +

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (EC 2.7.1.148)

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase. EC 2.7.1.148.. 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol

4-(dimethylamino)phenylazoxybenzene reductase (EC 1.7.1.11)

4-(dimethylamino)phenylazoxybenzene reductase. EC 1.7.1.11.. 4-(dimethylamino)azobenzene + NADP(+) + H2O =

4-(gamma-glutamylamino)butanal dehydrogenase (EC 1.2.1.99)

4-(gamma-glutamylamino)butanal dehydrogenase. EC 1.2.1.99.. (1) 4-(gamma-L-glutamylamino)butanal + NAD(+) + H2O = 4-(gamma-L-

4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] (EC 1.14.14.13)

4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein]. EC 1.14.14.13.. 4-(gamma-L-glutamylamino)butanoyl-[BtrI ACP] + FMNH2 + O2 = 4-(gamma-L-

4-(hydroxymethyl)benzenesulfonate dehydrogenase (EC 1.1.1.257)

4-(hydroxymethyl)benzenesulfonate dehydrogenase. EC 1.1.1.257.. 4-(hydroxymethyl)benzenesulfonate + NAD(+) = 4-formylbenzenesulfonate +

4-acetamidobutyrate deacetylase (EC 3.5.1.63)

4-acetamidobutyrate deacetylase. EC 3.5.1.63.. 4-acetamidobutanoate + H2O = 4-aminobutanoate + acetate.

4-acetamidobutyryl-CoA deacetylase (EC 3.5.1.51)

4-acetamidobutyryl-CoA deacetylase. EC 3.5.1.51.. 4-acetamidobutanoyl-CoA + H2O = 4-aminobutanoyl-CoA + acetate.

4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase (EC 3.2.1.141)

4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase. EC 3.2.1.141.. hydrolysis of (1->4)-alpha-D-glucosidic linkage in 4-alpha-D-[(1->4)-

4-alpha-glucanotransferase (EC 2.4.1.25)

4-alpha-glucanotransferase. EC 2.4.1.25.. Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an

4-amino-4-deoxychorismate mutase (EC 5.4.99.67)

4-amino-4-deoxychorismate mutase. EC 5.4.99.67.. 4-amino-4-deoxychorismate = 4-amino-4-deoxyprephenate.

4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming) (EC 2.6.1.123)

4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming). EC 2.6.1.123.. chorismate + 2 L-glutamine + H2O = 4-amino-4-deoxychorismate +

4-amino-4-deoxyprephenate dehydrogenase (EC 1.3.1.121)

4-amino-4-deoxyprephenate dehydrogenase. EC 1.3.1.121.. 4-amino-4-deoxyprephenate + NAD(+) = 3-(4-aminophenyl)pyruvate + CO2 +

4-amino-anhydrotetracycline N(4)-methyltransferase (EC 2.1.1.335)

4-amino-anhydrotetracycline N(4)-methyltransferase. EC 2.1.1.335.. (1) 4-amino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-

4-amino-L-phenylalanyl-[CmlP-peptidyl-carrier-protein] 3-hydroxylase (EC 1.14.99.65)

4-amino-L-phenylalanyl-[CmlP-peptidyl-carrier-protein] 3-hydroxylase. EC 1.14.99.65.. 4-amino-L-phenylalanyl-[peptidyl-carrier protein] + AH2 + O2 = (2R)-2-

4-aminobenzoate 1-monooxygenase (EC 1.14.13.27)

4-aminobenzoate 1-monooxygenase. EC 1.14.13.27.. (1) 4-aminobenzoate + NADH + O2 + 2 H(+) = 4-aminophenol + CO2 + NAD(+) +

4-aminobenzoate N-oxygenase (EC 1.14.99.68)

4-aminobenzoate N-oxygenase. EC 1.14.99.68.. 4-aminobenzoate + AH2 + 2 O2 = 4-nitrobenzoate + A + 2 H2O.

4-aminobutyrate--2-oxoglutarate transaminase (EC 2.6.1.19)

4-aminobutyrate--2-oxoglutarate transaminase. EC 2.6.1.19.. 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.

4-aminobutyrate--pyruvate transaminase (EC 2.6.1.96)

4-aminobutyrate--pyruvate transaminase. EC 2.6.1.96.. (1) 4-aminobutanoate + pyruvate = succinate semialdehyde + L-alanine.

4-carboxy-3-alkylbut-2-enoyl-[ACP] decarboxylase (EC 4.1.1.125)

4-carboxy-3-alkylbut-2-enoyl-[ACP] decarboxylase. EC 4.1.1.125.. a 4-carboxy-3-alkylbut-(2E)-enoyl-[ACP] + H(+) = a 3-alkylbut-(2E)-enoyl-

4-carboxymethyl-4-methylbutenolide mutase (EC 5.4.99.14)

4-carboxymethyl-4-methylbutenolide mutase. EC 5.4.99.14.. 4-methylmuconolactone = 3-methylmuconolactone.

4-carboxymuconolactone decarboxylase (EC 4.1.1.44)

4-carboxymuconolactone decarboxylase. EC 4.1.1.44.. (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H(+) = (4,5-dihydro-

4-chlorobenzoate dehalogenase (EC 3.8.1.6)

4-chlorobenzoate dehalogenase. EC 3.8.1.6.. 4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride + H(+).

4-chlorobenzoate--CoA ligase (EC 6.2.1.33)

4-chlorobenzoate--CoA ligase. EC 6.2.1.33.. 4-chlorobenzoate + ATP + CoA = 4-chlorobenzoyl-CoA + AMP + diphosphate.

4-chlorobenzoyl-CoA dehalogenase (EC 3.8.1.7)

4-chlorobenzoyl-CoA dehalogenase. EC 3.8.1.7.. 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl-CoA + chloride + H(+).

4-chlorophenylacetate 3,4-dioxygenase (EC 1.14.12.9)

4-chlorophenylacetate 3,4-dioxygenase. EC 1.14.12.9.. 4-chlorophenylacetate + NADH + O2 = 3,4-dihydroxyphenylacetate +

4-coumarate hydratase/lyase (EC 4.1.2.66)

4-coumarate hydratase/lyase. EC 4.1.2.66.. (E)-4-coumarate + H2O = 4-hydroxybenzaldehyde + acetate.

4-coumarate--CoA ligase (EC 6.2.1.12)

4-coumarate--CoA ligase. EC 6.2.1.12.. (E)-4-coumarate + ATP + CoA = (E)-4-coumaroyl-CoA + AMP + diphosphate.

4-coumaroyl-homoserine lactone synthase (EC 2.3.1.229)

4-coumaroyl-homoserine lactone synthase. EC 2.3.1.229.. 4-coumaroyl-CoA + S-adenosyl-L-methionine = N-(4-coumaroyl)-L-homoserine

4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase (EC 3.5.1.n3)

4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase. EC 3.5.1.n3.. 4-deoxy-4-formamido-alpha-L-arabinopyranosyl di-trans,octa-

4-deoxy-4-sulfo-D-erythrose isomerase (EC 5.3.1.37)

4-deoxy-4-sulfo-D-erythrose isomerase. EC 5.3.1.37.. 4-deoxy-4-sulfo-D-erythrose = 4-deoxy-4-sulfo-D-erythrulose.

4-dimethylallyltryptophan N-methyltransferase (EC 2.1.1.261)

4-dimethylallyltryptophan N-methyltransferase. EC 2.1.1.261.. 4-(3-methylbut-2-enyl)-L-tryptophan + S-adenosyl-L-methionine =

4-dimethylallyltryptophan synthase (EC 2.5.1.34)

4-dimethylallyltryptophan synthase. EC 2.5.1.34.. dimethylallyl diphosphate + L-tryptophan = 4-(3-methylbut-2-enyl)-L-

4-epi-cubebol synthase (EC 4.2.3.170)

4-epi-cubebol synthase. EC 4.2.3.170.. (2E,6E)-farnesyl diphosphate + H2O = 4-epi-cubebol + diphosphate.

4-formylbenzenesulfonate dehydrogenase (EC 1.2.1.62)

4-formylbenzenesulfonate dehydrogenase. EC 1.2.1.62.. 4-formylbenzenesulfonate + NAD(+) + H2O = 4-sulfobenzoate + NADH +

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase (EC 2.4.1.152)

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase. EC 2.4.1.152.. a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-

4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16)

4-hydroxy-2-oxoglutarate aldolase. EC 4.1.3.16.. (1) (4R)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate.

4-hydroxy-2-oxoheptanedioate aldolase (EC 4.1.2.52)

4-hydroxy-2-oxoheptanedioate aldolase. EC 4.1.2.52.. 4-hydroxy-2-oxoheptanedioate = succinate semialdehyde + pyruvate.

4-hydroxy-2-oxohexanoate aldolase (EC 4.1.3.43)

4-hydroxy-2-oxohexanoate aldolase. EC 4.1.3.43.. (S)-4-hydroxy-2-oxohexanoate = propanal + pyruvate.

4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.39)

4-hydroxy-2-oxovalerate aldolase. EC 4.1.3.39.. (S)-4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate.

4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase (EC 4.1.1.130)

4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase. EC 4.1.1.130.. a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + H(+) =

4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.7.4)

4-hydroxy-3-methylbut-2-enyl diphosphate reductase. EC 1.17.7.4.. (1) isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O =

4-hydroxy-3-polyprenylbenzoate 5-hydroxylase (EC 1.14.15.45)

4-hydroxy-3-polyprenylbenzoate 5-hydroxylase. EC 1.14.15.45.. a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + 2 reduced [2Fe-2S]-

4-hydroxy-3-polyprenylbenzoate decarboxylase (EC 4.1.1.98)

4-hydroxy-3-polyprenylbenzoate decarboxylase. EC 4.1.1.98.. a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + H(+) = a 2-(all-trans-

4-hydroxy-3-prenylbenzoate synthase (EC 1.13.12.23)

4-hydroxy-3-prenylbenzoate synthase. EC 1.13.12.23.. 3-dimethylallyl-4-hydroxymandelate + O2 = 3-dimethylallyl-4-

4-hydroxy-3-prenylphenylpyruvate oxygenase (EC 1.13.11.83)

4-hydroxy-3-prenylphenylpyruvate oxygenase. EC 1.13.11.83.. 3-dimethylallyl-4-hydroxyphenylpyruvate + O2 = 3-dimethylallyl-4-

4-hydroxy-4-methyl-2-oxoglutarate aldolase (EC 4.1.3.17)

4-hydroxy-4-methyl-2-oxoglutarate aldolase. EC 4.1.3.17.. (1) 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate.

4-hydroxy-6-methylpretetramide 12a-monooxygenase (EC 1.14.13.233)

4-hydroxy-6-methylpretetramide 12a-monooxygenase. EC 1.14.13.233.. 4-hydroxy-6-methylpretetramide + NADPH + O2 = 4-dedimethylamino-4-oxo-

4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside (EC 3.2.1.182)

4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside. EC 3.2.1.182.. (1) DIMBOA beta-D-glucoside + H2O = DIMBOA + D-glucose.

4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8)

4-hydroxy-tetrahydrodipicolinate reductase. EC 1.17.1.8.. (1) (S)-2,3,4,5-tetrahydrodipicolinate + NAD(+) + H2O = (2S,4S)-4-

4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7)

4-hydroxy-tetrahydrodipicolinate synthase. EC 4.3.3.7.. L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-

4-hydroxyacetophenone monooxygenase (EC 1.14.13.84)

4-hydroxyacetophenone monooxygenase. EC 1.14.13.84.. 4'-hydroxyacetophenone + NADPH + O2 + H(+) = 4-acetoxyphenol + NADP(+) +

4-hydroxybenzaldehyde dehydrogenase (NAD(+)) (EC 1.2.1.64)

4-hydroxybenzaldehyde dehydrogenase (NAD(+)). EC 1.2.1.64.. 4-hydroxybenzaldehyde + NAD(+) + H2O = 4-hydroxybenzoate + NADH + 2 H(+).