Biochemistry & Enzymes

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Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

Enzymes A-Z

Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.

tRNA nucleotidyltransferase (EC 2.7.7.56)

tRNA nucleotidyltransferase. EC 2.7.7.56.. tRNA(n+1) + phosphate = tRNA(n) + a ribonucleoside 5'-diphosphate.

tRNA pseudouridine(13) synthase (EC 5.4.99.27)

tRNA pseudouridine(13) synthase. EC 5.4.99.27.. uridine(13) in tRNA = pseudouridine(13) in tRNA.

tRNA pseudouridine(31) synthase (EC 5.4.99.42)

tRNA pseudouridine(31) synthase. EC 5.4.99.42.. uridine(31) in tRNA = pseudouridine(31) in tRNA.

tRNA pseudouridine(32) synthase (EC 5.4.99.28)

tRNA pseudouridine(32) synthase. EC 5.4.99.28.. uridine(32) in tRNA = pseudouridine(32) in tRNA.

tRNA pseudouridine(38-40) synthase (EC 5.4.99.12)

tRNA pseudouridine(38-40) synthase. EC 5.4.99.12.. uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA.

tRNA pseudouridine(38/39) synthase (EC 5.4.99.45)

tRNA pseudouridine(38/39) synthase. EC 5.4.99.45.. uridine(38/39) in tRNA = pseudouridine(38/39) in tRNA.

tRNA pseudouridine(55) synthase (EC 5.4.99.25)

tRNA pseudouridine(55) synthase. EC 5.4.99.25.. uridine(55) in tRNA = pseudouridine(55) in tRNA.

tRNA pseudouridine(65) synthase (EC 5.4.99.26)

tRNA pseudouridine(65) synthase. EC 5.4.99.26.. uridine(65) in tRNA = pseudouridine(65) in tRNA.

tRNA uracil 4-sulfurtransferase (EC 2.8.1.4)

tRNA uracil 4-sulfurtransferase. EC 2.8.1.4.. [ThiI sulfur-carrier protein]-S-sulfanyl-L-cysteine + a uridine in tRNA +

tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase (EC 2.8.4.3)

tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase. EC 2.8.4.3.. N(6)-dimethylallyladenosine(37) in tRNA + (sulfur carrier)-SH + AH2 +

tRNA-5-methyluridine(54) 2-sulfurtransferase (EC 2.8.1.15)

tRNA-5-methyluridine(54) 2-sulfurtransferase. EC 2.8.1.15.. [TtuB sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate +

tRNA-5-taurinomethyluridine 2-sulfurtransferase (EC 2.8.1.14)

tRNA-5-taurinomethyluridine 2-sulfurtransferase. EC 2.8.1.14.. 5-taurinomethyluridine(34) in tRNA + S-sulfanyl-L-cysteinyl-[protein] +

tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)] (EC 1.3.1.88)

tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]. EC 1.3.1.88.. (1) 5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA +

tRNA-dihydrouridine(20) synthase [NAD(P)(+)] (EC 1.3.1.91)

tRNA-dihydrouridine(20) synthase [NAD(P)(+)]. EC 1.3.1.91.. (1) 5,6-dihydrouridine(20) in tRNA + NADP(+) = uridine(20) in tRNA +

tRNA-dihydrouridine(20a/20b) synthase [NAD(P)(+)] (EC 1.3.1.90)

tRNA-dihydrouridine(20a/20b) synthase [NAD(P)(+)]. EC 1.3.1.90.. (1) 5,6-dihydrouridine(20a) in tRNA + NADP(+) = uridine(20a) in tRNA +

tRNA-dihydrouridine(47) synthase [NAD(P)(+)] (EC 1.3.1.89)

tRNA-dihydrouridine(47) synthase [NAD(P)(+)]. EC 1.3.1.89.. (1) 5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA +

tRNA-guanine(15) transglycosylase (EC 2.4.2.48)

tRNA-guanine(15) transglycosylase. EC 2.4.2.48.. guanosine(15) in tRNA + 7-cyano-7-carbaguanine = 7-cyano-7-

tRNA-guanosine(34) preQ1 transglycosylase (EC 2.4.2.29)

tRNA-guanosine(34) preQ1 transglycosylase. EC 2.4.2.29.. 7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA = 7-aminomethyl-7-

tRNA-guanosine(34) queuine transglycosylase (EC 2.4.2.64)

tRNA-guanosine(34) queuine transglycosylase. EC 2.4.2.64.. guanosine(34) in tRNA + queuine = queuosine(34) in tRNA + guanine.

tRNA-intron lyase (EC 4.6.1.16)

tRNA-intron lyase. EC 4.6.1.16.. pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA

tRNA-queuosine alpha-mannosyltransferase (EC 2.4.1.110)

tRNA-queuosine alpha-mannosyltransferase. EC 2.4.1.110.. queuosine(34) in tRNA(Asp) + GDP-alpha-D-mannose = O-4''-alpha-D-

tRNA-uridine 2-sulfurtransferase (EC 2.8.1.13)

tRNA-uridine 2-sulfurtransferase. EC 2.8.1.13.. S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA + AH2 + ATP =

tRNA-uridine aminocarboxypropyltransferase (EC 2.5.1.25)

tRNA-uridine aminocarboxypropyltransferase. EC 2.5.1.25.. a uridine in tRNA + S-adenosyl-L-methionine = a 3-[(3S)-3-amino-3-

tRNA:m(4)X modification enzyme (EC 2.1.1.225)

tRNA:m(4)X modification enzyme. EC 2.1.1.225.. (1) cytidine(4) in tRNA(Pro) + S-adenosyl-L-methionine = 2'-O-

tRNA(adenine(34)) deaminase (EC 3.5.4.33)

tRNA(adenine(34)) deaminase. EC 3.5.4.33.. adenosine(34) in tRNA + H2O + H(+) = inosine(34) in tRNA + NH4(+).

tRNA(Ala)(adenine(37)) deaminase (EC 3.5.4.34)

tRNA(Ala)(adenine(37)) deaminase. EC 3.5.4.34.. adenosine(37) in tRNA(Ala) + H2O + H(+) = inosine(37) in tRNA(Ala) +

tRNA(cytosine(8)) deaminase (EC 3.5.4.35)

tRNA(cytosine(8)) deaminase. EC 3.5.4.35.. cytidine(8) in tRNA + H2O + H(+) = uridine(8) in tRNA + NH4(+).

tRNA(His) guanylyltransferase (EC 2.7.7.79)

tRNA(His) guanylyltransferase. EC 2.7.7.79.. a 5'-end ribonucleotide-tRNA(His) + GTP + ATP + H2O = a 5'-end phospho-

tRNA(Ile)-lysidine synthetase (EC 6.3.4.19)

tRNA(Ile)-lysidine synthetase. EC 6.3.4.19.. cytidine(34) in tRNA(Ile2) + L-lysine + ATP = lysidine(34) in tRNA(Ile2)

tRNA(Ile)(2)-agmatinylcytidine synthase (EC 6.3.4.22)

tRNA(Ile)(2)-agmatinylcytidine synthase. EC 6.3.4.22.. cytidine(34) in tRNA(Ile2) + agmatine + ATP + H2O =

tRNA(Met) cytidine acetyltransferase (EC 2.3.1.193)

tRNA(Met) cytidine acetyltransferase. EC 2.3.1.193.. cytidine(34) in elongator tRNA(Met) + acetyl-CoA + ATP + H2O = N(4)-

tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase (EC 2.5.1.114)

tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase. EC 2.5.1.114.. 4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine =

tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase (EC 1.14.11.42)

tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase. EC 1.14.11.42.. 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + 2-oxoglutarate

tRNA(Phe) [7-(3-amino-3-carboxypropyl)wyosine(37)-O]-methyltransferase (EC 2.1.1.290)

tRNA(Phe) [7-(3-amino-3-carboxypropyl)wyosine(37)-O]-methyltransferase. EC 2.1.1.290.. 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-

tRNA(Phe) {7-[3-amino-3-(methoxycarbonyl)propyl]wyosine(37)-N}- (EC 2.3.1.231)

tRNA(Phe) {7-[3-amino-3-(methoxycarbonyl)propyl]wyosine(37)-N}-. EC 2.3.1.231.. 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) +

tRNA(Phe) 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4)]- (EC 2.1.1.282)

tRNA(Phe) 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4)]-. EC 2.1.1.282.. 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) +

tRNA(Ser) (uridine(44)-2'-O)-methyltransferase (EC 2.1.1.211)

tRNA(Ser) (uridine(44)-2'-O)-methyltransferase. EC 2.1.1.211.. uridine(44) in tRNA(Ser) + S-adenosyl-L-methionine = 2'-O-

tRNA(Thr) (cytosine(32)-N(3))-methyltransferase (EC 2.1.1.268)

tRNA(Thr) (cytosine(32)-N(3))-methyltransferase. EC 2.1.1.268.. (1) cytidine(32) in tRNA(Thr) + S-adenosyl-L-methionine = N(3)-

tRNA1(Val) (adenine(37)-N(6))-methyltransferase (EC 2.1.1.223)

tRNA1(Val) (adenine(37)-N(6))-methyltransferase. EC 2.1.1.223.. adenosine(37) in tRNA1(Val) + S-adenosyl-L-methionine = N(6)-

tRNAmet cytidine acetate ligase (EC 6.3.1.22)

tRNAmet cytidine acetate ligase. EC 6.3.1.22.. cytidine(34) in elongator tRNA(Met) + acetate + ATP = N(4)-

tropine acyltransferase (EC 2.3.1.185)

tropine acyltransferase. EC 2.3.1.185.. tropine + an acyl-CoA = an O-acyltropine + CoA + H(+).

tropinesterase (EC 3.1.1.10)

tropinesterase. EC 3.1.1.10.. atropine + H2O = tropate + tropine + H(+).

tropinone reductase I (EC 1.1.1.206)

tropinone reductase I. EC 1.1.1.206.. tropine + NADP(+) = tropinone + NADPH + H(+).

tropinone reductase II (EC 1.1.1.236)

tropinone reductase II. EC 1.1.1.236.. pseudotropine + NADP(+) = tropinone + NADPH + H(+).

tropomyosin kinase (EC 2.7.11.28)

tropomyosin kinase. EC 2.7.11.28.. ATP + [tropomyosin] = ADP + [tropomyosin] phosphate.

trypanothione synthase (EC 6.3.1.9)

trypanothione synthase. EC 6.3.1.9.. (1) spermidine + glutathione + ATP = glutathionylspermidine + ADP +

trypanothione-disulfide reductase (EC 1.8.1.12)

trypanothione-disulfide reductase. EC 1.8.1.12.. trypanothione + NADP(+) = trypanothione disulfide + NADPH + H(+).

tryprostatin B 6-hydroxylase (EC 1.14.14.118)

tryprostatin B 6-hydroxylase. EC 1.14.14.118.. tryprostatin B + reduced [NADPH--hemoprotein reductase] + O2 =

tryprostatin B synthase (EC 2.5.1.106)

tryprostatin B synthase. EC 2.5.1.106.. brevianamide F + dimethylallyl diphosphate = tryprostatin B +

trypsin (EC 3.4.21.4)

trypsin. EC 3.4.21.4.. Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

tryptamine 4-monooxygenase (EC 1.14.99.59)

tryptamine 4-monooxygenase. EC 1.14.99.59.. tryptamine + AH2 + O2 = 4-hydroxytryptamine + A + H2O.

tryptamine 5-hydroxylase (EC 1.14.14.186)

tryptamine 5-hydroxylase. EC 1.14.14.186.. tryptamine + reduced [NADPH--hemoprotein reductase] + O2 = serotonin +

tryptase (EC 3.4.21.59)

tryptase. EC 3.4.21.59.. Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa, but with more restricted

tryptophan 2-C-methyltransferase (EC 2.1.1.106)

tryptophan 2-C-methyltransferase. EC 2.1.1.106.. L-tryptophan + S-adenosyl-L-methionine = 2-methyl-L-tryptophan +

tryptophan 2-monooxygenase (EC 1.13.12.3)

tryptophan 2-monooxygenase. EC 1.13.12.3.. L-tryptophan + O2 = indole-3-acetamide + CO2 + H2O.

tryptophan 2,3-dioxygenase (EC 1.13.11.11)

tryptophan 2,3-dioxygenase. EC 1.13.11.11.. L-tryptophan + O2 = N-formyl-L-kynurenine.

tryptophan 2'-dioxygenase (EC 1.13.99.3)

tryptophan 2'-dioxygenase. EC 1.13.99.3.. L-tryptophan + O2 + H(+) = 3-indoleglycolaldehyde + NH4(+) + CO2.

tryptophan 5-brominase (NADPH) (EC 1.14.19.82)

tryptophan 5-brominase (NADPH). EC 1.14.19.82.. bromide + L-tryptophan + NADPH + O2 + 2 H(+) = 5-bromo-L-tryptophan +

tryptophan 5-halogenase (EC 1.14.19.58)

tryptophan 5-halogenase. EC 1.14.19.58.. L-tryptophan + FADH2 + chloride + O2 = 5-chloro-L-tryptophan + FAD +

tryptophan 5-monooxygenase (EC 1.14.16.4)

tryptophan 5-monooxygenase. EC 1.14.16.4.. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 =