Enzymes A-Z
Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.
Enzymes A-Z
Complete database of 6965 enzymes with EC numbers, catalytic activities, alternative names, and UniProt cross-references. Browse by EC class or search for specific enzymes.
thiosulfate--thiol sulfurtransferase (EC 2.8.1.3)
thiosulfate--thiol sulfurtransferase. EC 2.8.1.3.. thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide +
threo-3-hydroxy-D-aspartate ammonia-lyase (EC 4.3.1.27)
threo-3-hydroxy-D-aspartate ammonia-lyase. EC 4.3.1.27.. (3R)-3-hydroxy-D-aspartate = oxaloacetate + NH4(+).
threo-3-hydroxy-L-aspartate ammonia-lyase (EC 4.3.1.16)
threo-3-hydroxy-L-aspartate ammonia-lyase. EC 4.3.1.16.. (3S)-3-hydroxy-L-aspartate = oxaloacetate + NH4(+).
threonine ammonia-lyase (EC 4.3.1.19)
threonine ammonia-lyase. EC 4.3.1.19.. L-threonine = 2-oxobutanoate + NH4(+).
threonine racemase (EC 5.1.1.6)
threonine racemase. EC 5.1.1.6.. L-threonine = D-threonine.
threonine synthase (EC 4.2.3.1)
threonine synthase. EC 4.2.3.1.. O-phospho-L-homoserine + H2O = L-threonine + phosphate.
threonine--tRNA ligase (EC 6.1.1.3)
threonine--tRNA ligase. EC 6.1.1.3.. tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate
threonine-phosphate decarboxylase (EC 4.1.1.81)
threonine-phosphate decarboxylase. EC 4.1.1.81.. O-phospho-L-threonine + H(+) = (R)-1-aminopropan-2-yl phosphate + CO2.
thrombin (EC 3.4.21.5)
thrombin. EC 3.4.21.5.. Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and
thromboxane-A synthase (EC 5.3.99.5)
thromboxane-A synthase. EC 5.3.99.5.. prostaglandin H2 = thromboxane A2.
thujopsene synthase (EC 4.2.3.79)
thujopsene synthase. EC 4.2.3.79.. (2E,6E)-farnesyl diphosphate = (+)-thujopsene + diphosphate.
thymidine kinase (EC 2.7.1.21)
thymidine kinase. EC 2.7.1.21.. thymidine + ATP = dTMP + ADP + H(+).
thymidine phosphorylase (EC 2.4.2.4)
thymidine phosphorylase. EC 2.4.2.4.. thymidine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + thymine.
thymidine-triphosphatase (EC 3.6.1.39)
thymidine-triphosphatase. EC 3.6.1.39.. dTTP + H2O = dTDP + phosphate + H(+).
thymidylate 5'-phosphatase (EC 3.1.3.35)
thymidylate 5'-phosphatase. EC 3.1.3.35.. dTMP + H2O = thymidine + phosphate.
thymidylate synthase (EC 2.1.1.45)
thymidylate synthase. EC 2.1.1.45.. dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate = 7,8-dihydrofolate +
thymidylate synthase (FAD) (EC 2.1.1.148)
thymidylate synthase (FAD). EC 2.1.1.148.. dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADPH + H(+) = dTMP
thymine dioxygenase (EC 1.14.11.6)
thymine dioxygenase. EC 1.14.11.6.. thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2.
thymine-DNA glycosylase (EC 3.2.2.29)
thymine-DNA glycosylase. EC 3.2.2.29.. Hydrolyzes mismatched double-stranded DNA and polynucleotides, releasing
thyroid-hormone transaminase (EC 2.6.1.26)
thyroid-hormone transaminase. EC 2.6.1.26.. 3,3',5-triiodo-L-thyronine + 2-oxoglutarate = 3,5,3'-triiodothyropyruvate
thyroxine 5-deiodinase (EC 1.21.99.3)
thyroxine 5-deiodinase. EC 1.21.99.3.. 3,3',5'-triiodo-L-thyronine + iodide + A + H(+) = L-thyroxine + AH2.
thyroxine 5'-deiodinase (EC 1.21.99.4)
thyroxine 5'-deiodinase. EC 1.21.99.4.. 3,3',5-triiodo-L-thyronine + iodide + A + H(+) = L-thyroxine + AH2.
thyroxine sulfotransferase (EC 2.8.2.n2)
thyroxine sulfotransferase. EC 2.8.2.n2.. thyroxine + 3'-phosphoadenylyl sulfate = thyroxine sulfate + adenosine
tirucalladienol synthase (EC 5.4.99.56)
tirucalladienol synthase. EC 5.4.99.56.. (S)-2,3-epoxysqualene = tirucalla-7,24-dien-3beta-ol.
tissue kallikrein (EC 3.4.21.35)
tissue kallikrein. EC 3.4.21.35.. Preferential cleavage of Arg-|-Xaa bonds in small molecule substrates.
tocopherol C-methyltransferase (EC 2.1.1.95)
tocopherol C-methyltransferase. EC 2.1.1.95.. (1) gamma-tocopherol + S-adenosyl-L-methionine = (+)-alpha-tocopherol +
tocopherol cyclase (EC 5.5.1.24)
tocopherol cyclase. EC 5.5.1.24.. (1) delta-tocopherol = 2-methyl-6-phytyl-1,4-benzene-1,4-diol.
togavirin (EC 3.4.21.90)
togavirin. EC 3.4.21.90.. Autocatalytic release of the core protein from the N-terminus of the
toluene 2-monooxygenase (EC 1.14.13.243)
toluene 2-monooxygenase. EC 1.14.13.243.. (1) toluene + NADH + O2 + H(+) = 2-hydroxytoluene + NAD(+) + H2O.
toluene 4-monooxygenase (EC 1.14.13.236)
toluene 4-monooxygenase. EC 1.14.13.236.. toluene + NADH + O2 + H(+) = 4-methylphenol + NAD(+) + H2O.
toluene dioxygenase (EC 1.14.12.11)
toluene dioxygenase. EC 1.14.12.11.. toluene + NADH + O2 + H(+) = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol
toluene methyl-monooxygenase (EC 1.14.15.26)
toluene methyl-monooxygenase. EC 1.14.15.26.. (1) toluene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = benzyl
torosachrysone 7,10'-coupling laccase (EC 1.10.3.18)
torosachrysone 7,10'-coupling laccase. EC 1.10.3.18.. 4 (R)-torosachrysone + O2 = 2 phlegmacin + 2 H2O + 2 H(+).
torosachrysone-coupling peroxygenase (EC 1.11.2.7)
torosachrysone-coupling peroxygenase. EC 1.11.2.7.. 2 (R)-torosachrysone + H2O2 = phlegmacin + 2 H2O + H(+).
torulene dioxygenase (EC 1.13.11.59)
torulene dioxygenase. EC 1.13.11.59.. torulene + O2 = 4'-apo-beta-carotenal + 3-methyl-2-butenal.
toxoflavin synthase (EC 2.1.1.349)
toxoflavin synthase. EC 2.1.1.349.. (1) 1,6-didemethyltoxoflavin + S-adenosyl-L-methionine = reumycin +
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20)
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase. EC 1.3.1.20.. (1) (1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP(+) = catechol + NADPH +
trans-2-decenoyl-[acyl-carrier-protein] isomerase (EC 5.3.3.14)
trans-2-decenoyl-[acyl-carrier-protein] isomerase. EC 5.3.3.14.. (2E)-decenoyl-[ACP] = (3Z)-decenoyl-[ACP].
trans-2-enoyl-CoA reductase (NAD(+)) (EC 1.3.1.44)
trans-2-enoyl-CoA reductase (NAD(+)). EC 1.3.1.44.. a 2,3-saturated acyl-CoA + NAD(+) = a (2E)-enoyl-CoA + NADH + H(+).
trans-2-enoyl-CoA reductase (NADPH) (EC 1.3.1.38)
trans-2-enoyl-CoA reductase (NADPH). EC 1.3.1.38.. a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+).
trans-2,3-dihydro-3-hydroxyanthranilate isomerase (EC 5.3.3.17)
trans-2,3-dihydro-3-hydroxyanthranilate isomerase. EC 5.3.3.17.. (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxyate = (1R,6S)-6-
trans-2,3-dihydro-3-hydroxyanthranilic acid synthase (EC 3.3.2.15)
trans-2,3-dihydro-3-hydroxyanthranilic acid synthase. EC 3.3.2.15.. (2S)-2-amino-4-deoxychorismate + H2O = (5S,6S)-6-amino-5-
trans-4-coumaroyl-CoA 2'-hydroxylase (EC 1.14.11.62)
trans-4-coumaroyl-CoA 2'-hydroxylase. EC 1.14.11.62.. (E)-4-coumaroyl-CoA + 2-oxoglutarate + O2 = (E)-2,4-dihydroxycinnamoyl-
trans-4-hydroxy-L-proline dehydratase (EC 4.2.1.172)
trans-4-hydroxy-L-proline dehydratase. EC 4.2.1.172.. trans-4-hydroxy-L-proline = (S)-1-pyrroline-5-carboxylate + H2O + H(+).
trans-4-hydroxycyclohexanecarboxylate dehydrogenase (EC 1.1.1.226)
trans-4-hydroxycyclohexanecarboxylate dehydrogenase. EC 1.1.1.226.. trans-4-hydroxycyclohexane-1-carboxylate + NAD(+) = 4-oxocyclohexane-1-
trans-acenaphthene-1,2-diol dehydrogenase (EC 1.10.1.1)
trans-acenaphthene-1,2-diol dehydrogenase. EC 1.10.1.1.. (+-)-trans-acenaphthene-1,2-diol + 2 NADP(+) = acenaphthene-1,2-dione +
trans-aconitate 2-methyltransferase (EC 2.1.1.144)
trans-aconitate 2-methyltransferase. EC 2.1.1.144.. trans-aconitate + S-adenosyl-L-methionine = (E)-3-(methoxycarbonyl)pent-
trans-aconitate 3-methyltransferase (EC 2.1.1.145)
trans-aconitate 3-methyltransferase. EC 2.1.1.145.. trans-aconitate + S-adenosyl-L-methionine = (E)-2-
trans-aconitate decarboxylase (EC 4.1.1.113)
trans-aconitate decarboxylase. EC 4.1.1.113.. trans-aconitate + H(+) = itaconate + CO2.
trans-anol O-methyltransferase (EC 2.1.1.279)
trans-anol O-methyltransferase. EC 2.1.1.279.. (1) (E)-anol + S-adenosyl-L-methionine = (E)-anethole + S-adenosyl-L-
trans-cinnamate 2-monooxygenase (EC 1.14.13.14)
trans-cinnamate 2-monooxygenase. EC 1.14.13.14.. (E)-cinnamate + NADPH + O2 + H(+) = trans-2-coumarate + NADP(+) + H2O.
trans-cinnamate 4-monooxygenase (EC 1.14.14.91)
trans-cinnamate 4-monooxygenase. EC 1.14.14.91.. (E)-cinnamate + reduced [NADPH--hemoprotein reductase] + O2 = (E)-4-
trans-epoxysuccinate hydrolase (EC 3.3.2.4)
trans-epoxysuccinate hydrolase. EC 3.3.2.4.. trans-2,3-epoxysuccinate + H2O = (2R,3S)-tartrate.
trans-feruloyl-CoA synthase (EC 6.2.1.34)
trans-feruloyl-CoA synthase. EC 6.2.1.34.. (1) (E)-ferulate + ATP + CoA = (E)-feruloyl-CoA + ADP + phosphate.
trans-L-3-hydroxyproline dehydratase (EC 4.2.1.77)
trans-L-3-hydroxyproline dehydratase. EC 4.2.1.77.. trans-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O.
trans-o-hydroxybenzylidenepyruvate hydratase-aldolase (EC 4.1.2.45)
trans-o-hydroxybenzylidenepyruvate hydratase-aldolase. EC 4.1.2.45.. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O = salicylaldehyde +
trans-resveratrol di-O-methyltransferase (EC 2.1.1.240)
trans-resveratrol di-O-methyltransferase. EC 2.1.1.240.. trans-resveratrol + 2 S-adenosyl-L-methionine = pterostilbene +
trans-zeatin O-beta-D-glucosyltransferase (EC 2.4.1.203)
trans-zeatin O-beta-D-glucosyltransferase. EC 2.4.1.203.. trans-zeatin + UDP-alpha-D-glucose = O-beta-D-glucosyl-trans-zeatin +
trans,polycis-decaprenyl diphosphate synthase (EC 2.5.1.86)
trans,polycis-decaprenyl diphosphate synthase. EC 2.5.1.86.. (2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate =
trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl (EC 2.5.1.88)
trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl. EC 2.5.1.88.. (1) (2Z,6E)-farnesyl diphosphate + 9 isopentenyl diphosphate =